Antimicrobial resistance prediction in Neisseria gonorrhoeae: current status and future prospects

D Golparian, M Unemo - Expert Review of Molecular Diagnostics, 2022 - Taylor & Francis
Introduction Several nucleic acid amplification tests (NAATs), mostly PCRs, to detect
antimicrobial resistance (AMR) determinants and predict AMR in Neisseria gonorrhoeae are …

Advances in genotypic antimicrobialresistance testing: a comprehensive review

B Duan, X Zeng, J Peng - Science China Life Sciences, 2024 - Springer
Antimicrobial resistance (AMR) represents a substantial threat to global public health,
complicating the treatment of common infections and leading to prolonged illness and …

Application of nanopore sequencing technology in the clinical diagnosis of infectious diseases

LL Zhang, C Zhang, JP Peng - Biomedical and Environmental Sciences, 2022 - Elsevier
Infectious diseases are an enormous public health burden and a growing threat to human
health worldwide. Emerging or classic recurrent pathogens, or pathogens with resistant …

MGS2AMR: a gene-centric mining of metagenomic sequencing data for pathogens and their antimicrobial resistance profile

PJ Van Camp, VBS Prasath, DB Haslam, A Porollo - Microbiome, 2023 - Springer
Background Identification of pathogenic bacteria from clinical specimens and evaluating
their antimicrobial resistance (AMR) are laborious tasks that involve in vitro cultivation …

[HTML][HTML] Advances in Host Depletion and Pathogen Enrichment Methods for Rapid Sequencing–Based Diagnosis of Bloodstream Infection

MSI Sajib, K Brunker, K Oravcova, P Everest… - The Journal of Molecular …, 2024 - Elsevier
Bloodstream infection is a major cause of morbidity and death worldwide. Timely and
appropriate treatment can reduce mortality among critically ill patients. Current diagnostic …

Multiplexed target enrichment enables efficient and in-depth analysis of antimicrobial resistome in metagenomes

Y Li, X Shi, Y Zuo, T Li, L Liu, Z Shen, J Shen… - Microbiology …, 2022 - Am Soc Microbiol
Antibiotic resistance genes (ARGs) pose a serious threat to public health and ecological
security in the 21st century. However, the resistome only accounts for a tiny fraction of …

Direct sequencing technologies for bacterial sexually transmitted infections

A Jennison, S Pasricha, F Azzato - Microbiology Australia, 2024 - CSIRO Publishing
There is an important role for direct sequencing of patient samples to complement traditional
culture-based methods for bacterial sexually transmitted infections (STIs), effectively …

Multigeographic clinical assessment of a molecular diagnostic assay for detection of key codons to predict decreased susceptibility or resistance to cephalosporins in …

L Wang, Y Li, L Xiu, L Hu, J Huang… - Antimicrobial Agents …, 2024 - journals.asm.org
Cephalosporin resistance in Neisseria gonorrhoeae has severely compromised the efficacy
of World Health Organization (WHO)-recommended therapies. This study aimed to …

Typing of Neisseria gonorrhoeae isolates in Shenzhen, China, from 2014 to 2018 reveals the shift of genotypes significantly associated with antimicrobial resistance

Y Li, Y Li, L Xiu, Y Zeng, C Zhang, L Sun… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
The growing antimicrobial resistance (AMR) in Neisseria gonorrhoeae is a serious global
threat to gonococcal therapy. Molecular typing is an ideal tool to reveal the association …

Development and Comprehensive Evaluation of Culture-Independent, Long Amplicon-Based Targeted Next-Generation Sequencing Methods for Predicting …

L Zhang, X Yu, C Zhang, X Zhang, H Huang… - Analytical …, 2024 - ACS Publications
The great variety of antimicrobial resistance (AMR) profiles among tuberculosis (TB) patients
necessitates a comprehensive detection method. This study developed culture-independent …