The use of neoadjuvant systemic therapy in the treatment of breast cancer patients is
increasing beyond the scope of locally advanced disease. Imaging provides important …

Each year more than 180,000 new cases of breast cancer are diagnosed in women in the
US If cancer is detected when small and local, treatment options are less dangerous …

PURPOSE: To determine if changes in the concentration of choline-containing compounds
(tCho) from before primary systemic therapy (PST) to within 24 hours after the first treatment …

Results of the proton magnetic resonance spectroscopy carried out on normal, benign
breast disease and locally advanced breast cancer patients are presented. The in-vivo MR …

Proton magnetic resonance spectroscopy (1H MRS) of the breast has been proposed as an
adjunct to the magnetic resonance imaging (MRI) examination to improve the specificity of …

▪ Abstract Magnetic resonance spectroscopy (MRS) has been used for more than two
decades to interrogate metabolite distributions in living cells and tissues. Techniques have …

This work describes a methodology for quantifying levels of total choline‐containing
compounds (tCho) in the breast using in vivo 1H MR spectroscopy (MRS) at high field (4 …

Purpose: To prospectively evaluate the diagnostic performance of magnetic resonance (MR)
spectroscopy in patients with suspicious lesions or biopsy-proved cancers at MR imaging by …

Specific genetic alterations during malignant transformation may induce the synthesis and
breakdown of choline phospholipids, mediating transduction of mitogenic signals. The high …

High‐resolution magic angle spinning (HR MAS) may develop into a new diagnostic tool for
studying intact tissue samples, and several types of cancer have been investigated with …