[HTML][HTML] Diversity and complexity of cell death: a historical review
Death is the inevitable fate of all living organisms, whether at the individual or cellular level.
For a long time, cell death was believed to be an undesirable but unavoidable final outcome …
For a long time, cell death was believed to be an undesirable but unavoidable final outcome …
[HTML][HTML] Involvement of astrocytes in Alzheimer's disease from a neuroinflammatory and oxidative stress perspective
RE González-Reyes, MO Nava-Mesa… - Frontiers in molecular …, 2017 - frontiersin.org
Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in
humans, but still no curative treatment has been developed. Although many explicative …
humans, but still no curative treatment has been developed. Although many explicative …
[HTML][HTML] Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy
Skeletal muscle regeneration depends on the correct expansion of resident quiescent stem
cells (satellite cells), a process that becomes less efficient with aging. Here, we show that …
cells (satellite cells), a process that becomes less efficient with aging. Here, we show that …
[HTML][HTML] Lipid peroxidation increases membrane tension, Piezo1 gating, and cation permeability to execute ferroptosis
The ongoing metabolic and microbicidal pathways that support and protect cellular life
generate potentially damaging reactive oxygen species (ROS). To counteract damage, cells …
generate potentially damaging reactive oxygen species (ROS). To counteract damage, cells …
[HTML][HTML] Calcium-overload-mediated tumor therapy by calcium peroxide nanoparticles
Calcium overload, characterized by an abnormal cytoplasm accumulation of free calcium
ions (Ca 2+), is a widely recognized cause of damage in numerous cell types and even of …
ions (Ca 2+), is a widely recognized cause of damage in numerous cell types and even of …
The genetics and pathology of mitochondrial disease
Mitochondria are double‐membrane‐bound organelles that are present in all nucleated
eukaryotic cells and are responsible for the production of cellular energy in the form of ATP …
eukaryotic cells and are responsible for the production of cellular energy in the form of ATP …
Redox regulation of NLRP3 inflammasomes: ROS as trigger or effector?
Significance: Inflammasomes are multiprotein complexes localized within the cytoplasm of
the cell that are responsible for the maturation of proinflammatory cytokines such as …
the cell that are responsible for the maturation of proinflammatory cytokines such as …
[HTML][HTML] New anti-cancer explorations based on metal ions
H Hu, Q Xu, Z Mo, X Hu, Q He, Z Zhang… - Journal of …, 2022 - Springer
Due to the urgent demand for more anti-cancer methods, the new applications of metal ions
in cancer have attracted increasing attention. Especially the three kinds of the new mode of …
in cancer have attracted increasing attention. Especially the three kinds of the new mode of …
[HTML][HTML] Cellular and molecular mechanisms of mitochondrial function
Mitochondria are membrane bound organelles present in almost all eukaryotic cells.
Responsible for orchestrating cellular energy production, they are central to the …
Responsible for orchestrating cellular energy production, they are central to the …
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
T Murakami, J Ockinger, J Yu, V Byles… - Proceedings of the …, 2012 - National Acad Sciences
The NLRP3 (nucleotide-binding domain, leucine-rich-repeat-containing family, pyrin domain-
containing 3) inflammasome mediates production of inflammatory mediators, such as IL-1β …
containing 3) inflammasome mediates production of inflammatory mediators, such as IL-1β …