Metal ion-directed functional metal–phenolic materials
Metal ions are ubiquitous in nature and play significant roles in assembling functional
materials in fields spanning chemistry, biology, and materials science. Metal–phenolic …
materials in fields spanning chemistry, biology, and materials science. Metal–phenolic …
Current and promising applications of Hf (IV)-based MOFs in clinical cancer therapy
X Chen, M Li, M Lin, C Lu, A Kumar, Y Pan… - Journal of Materials …, 2023 - pubs.rsc.org
Cancer is one of the greatest challenges in medical science today as it poses a serious
threat to human life. In view of this, myriad of therapeutic strategies are being developed for …
threat to human life. In view of this, myriad of therapeutic strategies are being developed for …
Phototheranostic metal-phenolic networks with antiexosomal PD-L1 enhanced ferroptosis for synergistic immunotherapy
Tumor-derived exosome can suppress dendritic cells (DCs) and T cells functions. Excessive
secretion of exosomal programmed death-ligand 1 (PD-L1) results in therapeutic resistance …
secretion of exosomal programmed death-ligand 1 (PD-L1) results in therapeutic resistance …
One-step integration of tumor microenvironment-responsive calcium and copper peroxides nanocomposite for enhanced chemodynamic/ion-interference therapy
B Liu, Y Bian, S Liang, M Yuan, S Dong, F He, S Gai… - ACS …, 2021 - ACS Publications
Recently, various metal peroxide nanomaterials have drawn increasing attention as an
efficient hydrogen peroxide (H2O2) self-supplying agent for enhanced tumor therapy …
efficient hydrogen peroxide (H2O2) self-supplying agent for enhanced tumor therapy …
Engineering radiosensitizer‐based metal‐phenolic networks potentiate STING pathway activation for advanced radiotherapy
Radiotherapy, a mainstay of first‐line cancer treatment, suffers from its high‐dose radiation‐
induced systemic toxicity and radioresistance caused by the immunosuppressive tumor …
induced systemic toxicity and radioresistance caused by the immunosuppressive tumor …
Biomineralized MnO2 Nanoplatforms Mediated Delivery of Immune Checkpoint Inhibitors with STING Pathway Activation to Potentiate Cancer Radio-Immunotherapy
Radiotherapy (RT), as one of the main methods in the clinical treatment of various malignant
tumors, would induce systemic immunotherapeutic effects by triggering immunogenic cell …
tumors, would induce systemic immunotherapeutic effects by triggering immunogenic cell …
Nanoparticle‐mediated radiotherapy remodels the tumor microenvironment to enhance antitumor efficacy
Radiotherapy (RT) uses ionizing radiation to eradicate localized tumors and, in rare cases,
control tumors outside of the irradiated fields via stimulating an antitumor immune response …
control tumors outside of the irradiated fields via stimulating an antitumor immune response …
Boosting checkpoint immunotherapy with biomaterials
The immune checkpoint blockade (ICB) therapy has revolutionized the field of cancer
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …
Chemotherapy mediated by biomimetic polymeric nanoparticles potentiates enhanced tumor immunotherapy via amplification of endoplasmic reticulum stress and …
Y Guo, Y Fan, Z Wang, G Li, M Zhan, J Gong… - Advanced …, 2022 - Wiley Online Library
Construction of multifunctional nanoplatforms to elevate chemotherapeutic efficacy and
induce long‐term antitumor immunity still remains to be an extreme challenge. Herein, the …
induce long‐term antitumor immunity still remains to be an extreme challenge. Herein, the …
Nanostructured particles assembled from natural building blocks for advanced therapies
Advanced treatments based on immune system manipulation, gene transcription and
regulation, specific organ and cell targeting, and/or photon energy conversion have …
regulation, specific organ and cell targeting, and/or photon energy conversion have …