Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis

E Rossi, R La Rosa, JA Bartell, RL Marvig… - Nature Reviews …, 2021 - nature.com
Intense genome sequencing of Pseudomonas aeruginosa isolates from cystic fibrosis (CF)
airways has shown inefficient eradication of the infecting bacteria, as well as previously …

Bacterial siderophores in community and host interactions

J Kramer, Ö Özkaya, R Kümmerli - Nature Reviews Microbiology, 2020 - nature.com
Iron is an essential trace element for most organisms. A common way for bacteria to acquire
this nutrient is through the secretion of siderophores, which are secondary metabolites that …

Competition for iron drives phytopathogen control by natural rhizosphere microbiomes

S Gu, Z Wei, Z Shao, VP Friman, K Cao, T Yang… - Nature …, 2020 - nature.com
Plant pathogenic bacteria cause high crop and economic losses to human societies,–.
Infections by such pathogens are challenging to control as they often arise through complex …

Microbial communities form rich extracellular metabolomes that foster metabolic interactions and promote drug tolerance

JSL Yu, C Correia-Melo, F Zorrilla… - Nature …, 2022 - nature.com
Microbial communities are composed of cells of varying metabolic capacity, and regularly
include auxotrophs that lack essential metabolic pathways. Through analysis of auxotrophs …

Spatial structure, cooperation and competition in biofilms

CD Nadell, K Drescher, KR Foster - Nature Reviews Microbiology, 2016 - nature.com
Bacteria often live within matrix-embedded communities, termed biofilms, which are now
understood to be a major mode of microbial life. The study of biofilms has revealed their vast …

Pseudomonas aeruginosa evolutionary adaptation and diversification in cystic fibrosis chronic lung infections

C Winstanley, S O'Brien, MA Brockhurst - Trends in microbiology, 2016 - cell.com
Pseudomonas aeruginosa populations undergo a characteristic evolutionary adaptation
during chronic infection of the cystic fibrosis (CF) lung, including reduced production of …

Within-host evolution of bacterial pathogens

X Didelot, AS Walker, TE Peto, DW Crook… - Nature Reviews …, 2016 - nature.com
Whole-genome sequencing has opened the way for investigating the dynamics and
genomic evolution of bacterial pathogens during the colonization and infection of humans …

Transition metals and virulence in bacteria

LD Palmer, EP Skaar - Annual review of genetics, 2016 - annualreviews.org
Transition metals are required trace elements for all forms of life. Due to their unique
inorganic and redox properties, transition metals serve as cofactors for enzymes and other …

Gut to lung translocation and antibiotic mediated selection shape the dynamics of Pseudomonas aeruginosa in an ICU patient

RM Wheatley, JD Caballero, TE van der Schalk… - Nature …, 2022 - nature.com
Bacteria have the potential to translocate between sites in the human body, but the
dynamics and consequences of within-host bacterial migration remain poorly understood …

Superorganismality and caste differentiation as points of no return: how the major evolutionary transitions were lost in translation

JJ Boomsma, R Gawne - Biological Reviews, 2018 - Wiley Online Library
More than a century ago, William Morton Wheeler proposed that social insect colonies can
be regarded as superorganisms when they have morphologically differentiated reproductive …