Eurycoma longifolia Jack (known as tongkat ali), a popular traditional herbal medicine, is a
flowering plant of the family Simaroubaceae, native to Indonesia, Malaysia, Vietnam and …

Chronic myeloid leukemia (CML) is probably the most extensively studied human
malignancy. The discovery of the Philadelphia (Ph) chromosome in 19601 as the first …

Tissue-resident memory CD8+ T (TRM) cells are found at common sites of pathogen
exposure, where they elicit rapid and robust protective immune responses,. However, the …

Inflammasomes are innate immune sensors that respond to pathogen-and damage-
associated signals with caspase-1 activation, interleukin (IL)-1β and IL-18 secretion, and …

The majority of chimeric antigen receptor (CAR) T-cell research has focused on attacking
cancer cells. Here, we show that targeting the tumor-promoting, nontransformed stromal …

Animal cells harbour multiple innate effector mechanisms that inhibit virus replication. For
the pathogenic retrovirus human immunodeficiency virus type 1 (HIV-1), these include …

Genetic studies have established anaplastic lymphoma kinase (ALK), a cell surface receptor
tyrosine kinase, as a tractable molecular target in neuroblastoma. We describe …

The flow cytometry data in the original Fig. 1b were found to be flawed in that corresponding
IgG isotype control tracings for several of the plots differ by 1 log in fluorescence intensity …

Viruses have developed diverse non-immune strategies to counteract host-mediated
mechanisms that confer resistance to infection. The Vif (virion infectivity factor) proteins are …

Interleukin-17 (IL-17)-producing helper T (TH) cells, named as TH IL-17, TH17, or
inflammatory TH (THi), have been recently identified as a novel effector lineage. However …