Different Schiff bases—structure, importance and classification
E Raczuk, B Dmochowska, J Samaszko-Fiertek… - Molecules, 2022 - mdpi.com
Schiff bases are a vast group of compounds characterized by the presence of a double bond
linking carbon and nitrogen atoms, the versatility of which is generated in the many ways to …
linking carbon and nitrogen atoms, the versatility of which is generated in the many ways to …
Quinolines, a perpetual, multipurpose scaffold in medicinal chemistry
Quinoline is a versatile pharmacophore, a privileged scaffold and an outstanding fused
heterocyclic compound with a wide range of pharmacological prospective such as …
heterocyclic compound with a wide range of pharmacological prospective such as …
Updated information on antimicrobial activity of hydrazide–hydrazones
Ł Popiołek - International Journal of Molecular Sciences, 2021 - mdpi.com
Hydrazide–hydrazones possess a wide spectrum of bioactivity, including antibacterial,
antitubercular, antifungal, anticancer, anti-inflammatory, anticonvulsant, antidepressant …
antitubercular, antifungal, anticancer, anti-inflammatory, anticonvulsant, antidepressant …
Quinoline hydrazide/hydrazone derivatives: Recent insights on antibacterial activity and mechanism of action
S Verma, S Lal, R Narang, K Sudhakar - ChemMedChem, 2023 - Wiley Online Library
Antibiotics are becoming gradually ineffective due to drug resistance, leading to greater
difficulty in the treatment of infectious diseases. Therefore, the development of new chemical …
difficulty in the treatment of infectious diseases. Therefore, the development of new chemical …
Novel N-Acyl Hydrazone Compounds as Promising Anticancer Agents: Synthesis and Molecular Docking Studies
Y Biliz, B Hasdemir, H Başpınar Küçük… - ACS …, 2023 - ACS Publications
In this study, a new series of N-acyl hydrazones 7a-e, 8a-e, and 9a-e, starting from methyl δ-
oxo pentanoate with different substituted groups 1a-e, were synthesized as anticancer …
oxo pentanoate with different substituted groups 1a-e, were synthesized as anticancer …
[HTML][HTML] Synthesis and in vitro bioactivity study of new hydrazide-hydrazones of 5-bromo-2-iodobenzoic acid
Ł Popiołek, P Patrejko, M Gawrońska-Grzywacz… - Biomedicine & …, 2020 - Elsevier
In this study 14 novel hydrazide-hydrazones of 5-bromo-2-iodobenzoic acid (3-16) were
synthesized on the basis of condensation reaction. The chemical structure of obtained …
synthesized on the basis of condensation reaction. The chemical structure of obtained …
Modeling the DFT structural and reactivity studies of a pyrimidine-6-carboxylate derivative with reference to its wavefunction-dependent, MD simulations and …
M Smitha, YS Mary, YS Mary, G Serdaroglu… - Journal of Molecular …, 2021 - Elsevier
Spectroscopic, electronic and chemical properties and molecular docking simulations of
ethyl-2-(4-ethoxybenzylidene)-7-methyl-3-oxo-5-(4-benzyloxyphenyl)-2, 3-dihydro-5H-[1, 3] …
ethyl-2-(4-ethoxybenzylidene)-7-methyl-3-oxo-5-(4-benzyloxyphenyl)-2, 3-dihydro-5H-[1, 3] …
Substituent effect in salicylaldehyde 2-furoic acid hydrazones: Theoretical and experimental insights into DNA/BSA affinity modulation, antimicrobial and antioxidant …
The biological properties of five aroylhydrazones derived from salicylaldehyde and its 5-
substituted derivatives with 2-furoic acid hydrazide were thoroughly investigated. NMR …
substituted derivatives with 2-furoic acid hydrazide were thoroughly investigated. NMR …
Novel derivatives of 4-methyl-1, 2, 3-thiadiazole-5-carboxylic acid hydrazide: Synthesis, lipophilicity, and in vitro antimicrobial activity screening
K Paruch, Ł Popiołek, A Biernasiuk, A Berecka-Rycerz… - Applied Sciences, 2021 - mdpi.com
Bacterial infections, especially those caused by strains resistant to commonly used
antibiotics and chemotherapeutics, are still a current threat to public health. Therefore, the …
antibiotics and chemotherapeutics, are still a current threat to public health. Therefore, the …
Synthesis, structural characterization, and antimicrobial activity of novel ferrocene-N-acyl hydrazones designed by means of molecular simplification strategy …
JM dos Santos Filho, MVB de Souza Castro - Journal of Organometallic …, 2022 - Elsevier
The pursuit of new biological active and structurally diverse molecules is the main core of
medicinal chemistry, which can be achieved by means of different theoretical and …
medicinal chemistry, which can be achieved by means of different theoretical and …