Peripheral artery disease (PAD) is a common circulatory disorder of the lower limb arteries
that reduces functional capacity and quality of life of patients. Despite relatively effective …

Ischemia-reperfusion injury occurs when tissue is reperfused following a prolonged period
of ischemia. It is a subject of interest to plastic surgeons involved in replantation, free tissue …

Objective Acute limb ischemia (ALI), the most challenging form of ischemia-reperfusion
injury (IRI) in skeletal muscle tissue, leads to decreased skeletal muscle viability and limb …

Sprint exercise ability has been critical for survival. The remarkably high-power output levels
attained during sprint exercise are achieved through strong activation of anaerobic, and to a …

The interplay between implant design, biomaterial characteristics, and the local
microenvironment adjacent to the implant is of utmost importance for implant performance …

Mouse hind limb ischemia is the most common used preclinical model for peripheral arterial
disease and critical limb ischemia. This model is used to investigate the mechanisms of …

Ischemic diseases are conditions associated with the restriction or blockage of blood supply
to specific tissues. These conditions can cause moderate to severe complications in …

The redox homeostasis between hydrogen peroxide (H 2 O 2) and sulfur dioxide (SO 2) is
necessary to maintain the normal physiological function of biological system. However, Due …

Severe polytraumatic injury initiates a robust immune response. Broad immune dysfunction
in patients with such injuries has been well-documented; however, early biomarkers of …

Peripheral arterial disease (PAD) is a frequent and serious condition, potentially life-
threatening and leading to lower-limb amputation. Its pathophysiology is generally related to …