Abstract Chromosome 22q11. 2 deletion syndrome is a common syndrome also known as
DiGeorge syndrome and velocardiofacial syndrome. It occurs in approximately 1: 4000 …

Summary 22q11. 2 deletion syndrome is characterised by a well defined microdeletion that
is associated with a high risk of neuropsychiatric disorders, including intellectual disability …

Abstract The 22q11. 2 deletion (22q11DS) is a common chromosomal microdeletion and a
potent risk factor for psychotic illness. Prior studies reported widespread cortical changes in …

Importance Patients with 22q11. 2 deletion syndrome (22q11DS) have an elevated (25%)
risk of developing schizophrenia. Recent reports have suggested that a subgroup of children …

In the course of development, the brain undergoes a remarkable process of restructuring as
it adapts to the environment and becomes more efficient in processing information. A variety …

It has been widely accepted that the younger the age and/or immaturity of the organism, the
greater the brain plasticity, the young age plasticity privilege. This paper examines the …

It remains unclear if changes of the cerebral cortex occur gradually from childhood to
adulthood, or if adolescence marks a differential period of cortical development. In the …

Probing naturally-occurring, reciprocal genomic copy number variations (CNVs) may help us
understand mechanisms that underlie deviations from typical brain development. Cross …

Abstract 22q11. 2 Deletion syndrome has become an important model for understanding the
pathophysiology of neurodevelopmental conditions, particularly schizophrenia which …

Understanding the developmental etiology of autistic spectrum disorders, attention
deficit/hyperactivity disorder and schizophrenia remains a major challenge for establishing …