Recent advances in separation and analysis of chiral compounds

HL Qian, ST Xu, XP Yan - Analytical Chemistry, 2023 - ACS Publications
September 2020 to September 2022. Only some parts of quality studies were
representatively discussed due to the limitation of the policy of Analytical Chemistry. The …

Comprehensive review on chiral stationary phases in single-column simultaneous chiral–achiral HPLC separation methods

LA Papp, ZI Szabó, G Hancu, L Farczádi, E Mircia - Molecules, 2024 - mdpi.com
This comprehensive review explores the utilization of chiral stationary phases (CSPs) in the
context of single-column simultaneous chiral–achiral high-performance liquid …

Chiral resolution of (±)-flurbiprofen using molecularly imprinted hydrazidine-modified cellulose microparticles

HS AlSalem, M Monier, MA Abomuti… - International Journal of …, 2023 - Elsevier
Flurbiprofen (FP) is one of the non-steroidal anti-inflammatory drugs (NSAIDs) commonly
used to treat arthritic conditions. FP has two enantiomers: S-FP and R-FP. S-FP has potent …

Determination of chiral impurity of naproxen in different pharmaceutical formulations using polysaccharide-based stationary phases in reversed-phased mode

LA Papp, S Krizbai, M Dobó, G Hancu, ZI Szabó… - Molecules, 2022 - mdpi.com
A novel, validated, reversed-phase (RP), chiral high performance liquid chromatography
(HPLC) method was developed for the enantiopurity control analysis of naproxen, a …

Preparation of molecularly imprinted silica particles with amino functionality for chiral separation of (±)‐naproxen

AAH Bukhari - Chirality, 2023 - Wiley Online Library
Herein is the synthesis and effective use of an S‐naproxen (S‐NP) enantioselective
adsorbent material with amino functionality for the enantioseparation of a (±)‐NP racemic …

Enantioselective separation and determination of ibuprofen: Stereoselective pharmacokinetics, pharmacodynamics and analytical methods

VK Vashistha, T Kumar, S Yadav, DK Das - Chirality, 2024 - Wiley Online Library
Abstract Ibuprofen (IBP), the 29th most prescribed drug in the United States in 2019, is a
widely used nonsteroidal anti‐inflammatory drug (NSAID) comprising two enantiomers,(R) …

Tandem-Column High Performance Liquid Chromatography Separation of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

ME Marrazzo, JP Foley - Chromatographia, 2023 - Springer
A tandem-column liquid chromatographic method was developed to separate ten non-
steroidal anti-inflammatory drugs (Aceclofenac, Aspirin, Carprofen, Celecoxib, Diclofenac …

Vibrational Spectroscopic Features of Ibuprofen and Ketoprofen: IR and Raman Spectroscopy Combined with DFT Calculations

K Logacheva, P Gergelezhiu, E Raksha… - Physics of Particles and …, 2024 - Springer
Vibrational spectroscopic features of ibuprofen and ketoprofen (non-steroidal anti-
inflammatory drugs) were determined as a result of joint analysis of experimental and DFT …

Analysis of Naproxen in Rabbit Plasma by GC-MS Method

B Yilmaz - Journal of the Institute of Science and Technology, 2022 - dergipark.org.tr
Naproxen is one of the most used drugs today. Therefore, it is important to develop new and
simple methods for the determination of naproxen. The goal of this research is to develop a …

Applications of Tandem Column–Liquid Chromatography for the Achiral and Chiral Separation of Selected Classes of Pharmaceuticals

ME Marrazzo - 2024 - search.proquest.com
Tandem column-liquid chromatography (TC-LC) is a type of high performance liquid
chromatography (HPLC) that is designed to improve selectivity, resolution, and efficiency by …