Ketamine produces antidepressant effects in patients with treatment-resistant depression,
but its usefulness is limited by its psychotropic side effects. Ketamine is thought to act via …

Objective Epilepsy surgery fails to achieve seizure freedom in 30%–40% of cases. It is not
fully understood why some surgeries are unsuccessful. By comparing interictal …

A long-standing topic of interest in human neurosciences is the understanding of the
neurobiology underlying human cognition. Less commonly considered is to what extent …

Background Schizophrenia (SCZ) and bipolar disorder (BD) are severe psychiatric
conditions that can involve symptoms of psychosis and cognitive dysfunction. The 2 …

Stress following preterm birth can disrupt the emerging foundation of the neonatal brain. The
current study examined how structural brain development is affected by a stressful early …

Background Turner syndrome (TS) and Noonan syndrome (NS) are distinct genetic
conditions with highly similar physical and neurodevelopmental phenotypes. TS is caused …

Background Schizophrenia is a polygenic disorder associated with changes in brain
structure and function. Integrating macroscale brain features with microscale genetic data …

Individual differences in brain organization are an important biological factor for variation in
cognitive abilities among humans. Other species such as chimpanzees may similarly show a …

Psychiatric conditions show overlap in their symptoms, genetics and their involvement in
brain areas and circuits. Structural alterations in the brain have been found to run in parallel …

Preterm birth disrupts the emerging foundations of the brain's architecture, and the
continuum of early-life stress-provoked alterations reaches from a healthy adaptation with …