Genomic imprinting disorders: lessons on how genome, epigenome and environment interact

D Monk, DJG Mackay, T Eggermann, ER Maher… - Nature Reviews …, 2019 - nature.com
Genomic imprinting, the monoallelic and parent-of-origin-dependent expression of a subset
of genes, is required for normal development, and its disruption leads to human disease …

Epigenetic modifications in stress response genes associated with childhood trauma

S Jiang, L Postovit, A Cattaneo, EB Binder… - Frontiers in …, 2019 - frontiersin.org
Adverse childhood experiences (ACEs) may be referred to by other terms (eg, early life
adversity or stress and childhood trauma) and have a lifelong impact on mental and physical …

Intergenerational transmission of parental adverse childhood experiences and children's outcomes: A scoping review

L Zhang, JP Mersky, AMH Gruber… - Trauma, Violence, & …, 2023 - journals.sagepub.com
Adverse childhood experiences (ACEs) are among the leading environmental causes of
morbidity and mortality. Extending research on within-generation effects, more recent …

Developmental adaptation to stress: An evolutionary perspective

BJ Ellis, M Del Giudice - Annual review of psychology, 2019 - annualreviews.org
The assumption that early stress leads to dysregulation and impairment is widespread in
developmental science and informs prevailing models (eg, toxic stress). An alternative …

Praegnatio perturbatio—impact of endocrine-disrupting chemicals

V Padmanabhan, W Song… - Endocrine …, 2021 - academic.oup.com
The burden of adverse pregnancy outcomes such as preterm birth and low birth weight is
considerable across the world. Several risk factors for adverse pregnancy outcomes have …

Considerations toward an epigenetic and common pathways theory of mental disorder.

JT Nigg - Journal of Psychopathology and Clinical Science, 2023 - psycnet.apa.org
Psychopathology emerges from the dynamic interplay of physiological and mental
processes and ecological context. It can be seen as a failure of recursive, homeostatic …

Maternal caregiving and DNA methylation in human infants and children: Systematic review

L Provenzi, M Brambilla… - Genes, Brain and …, 2020 - Wiley Online Library
The integration of behavioral epigenetics' principles (eg, DNA methylation) into the study of
human infants' development has mainly focused on the effects of early adverse exposures …

Increases in maternal depressive symptoms during pregnancy and infant cortisol reactivity: mediation by placental corticotropin-releasing hormone

GR Rinne, JA Somers, IF Ramos, KM Ross… - Development and …, 2023 - cambridge.org
Background: Maternal depressive symptoms in pregnancy may affect offspring health
through prenatal programming of the hypothalamic–pituitary–adrenal (HPA) axis. The …

Intergenerational transmission of emotion dysregulation: Part II. Developmental origins of newborn neurobehavior

BD Ostlund, RD Vlisides-Henry, SE Crowell… - Development and …, 2019 - cambridge.org
We investigated whether neurobehavioral markers of risk for emotion dysregulation were
evident among newborns, as well as whether the identified markers were associated with …

Impact of parental adverse childhood experiences on offspring development in early head start: Parental adversity and offspring development

A Miccoli, J Song, M Romanowicz… - Journal of primary …, 2022 - journals.sagepub.com
Adverse childhood experiences (ACEs) are potentially traumatic events that can cause
lifelong suffering, with 1 out of 2 children in the United States experiencing at least 1 ACEs …