Genomic imprinting disorders: lessons on how genome, epigenome and environment interact
Genomic imprinting, the monoallelic and parent-of-origin-dependent expression of a subset
of genes, is required for normal development, and its disruption leads to human disease …
of genes, is required for normal development, and its disruption leads to human disease …
Epigenetic modifications in stress response genes associated with childhood trauma
Adverse childhood experiences (ACEs) may be referred to by other terms (eg, early life
adversity or stress and childhood trauma) and have a lifelong impact on mental and physical …
adversity or stress and childhood trauma) and have a lifelong impact on mental and physical …
Intergenerational transmission of parental adverse childhood experiences and children's outcomes: A scoping review
Adverse childhood experiences (ACEs) are among the leading environmental causes of
morbidity and mortality. Extending research on within-generation effects, more recent …
morbidity and mortality. Extending research on within-generation effects, more recent …
Developmental adaptation to stress: An evolutionary perspective
BJ Ellis, M Del Giudice - Annual review of psychology, 2019 - annualreviews.org
The assumption that early stress leads to dysregulation and impairment is widespread in
developmental science and informs prevailing models (eg, toxic stress). An alternative …
developmental science and informs prevailing models (eg, toxic stress). An alternative …
Praegnatio perturbatio—impact of endocrine-disrupting chemicals
V Padmanabhan, W Song… - Endocrine …, 2021 - academic.oup.com
The burden of adverse pregnancy outcomes such as preterm birth and low birth weight is
considerable across the world. Several risk factors for adverse pregnancy outcomes have …
considerable across the world. Several risk factors for adverse pregnancy outcomes have …
Considerations toward an epigenetic and common pathways theory of mental disorder.
JT Nigg - Journal of Psychopathology and Clinical Science, 2023 - psycnet.apa.org
Psychopathology emerges from the dynamic interplay of physiological and mental
processes and ecological context. It can be seen as a failure of recursive, homeostatic …
processes and ecological context. It can be seen as a failure of recursive, homeostatic …
Maternal caregiving and DNA methylation in human infants and children: Systematic review
L Provenzi, M Brambilla… - Genes, Brain and …, 2020 - Wiley Online Library
The integration of behavioral epigenetics' principles (eg, DNA methylation) into the study of
human infants' development has mainly focused on the effects of early adverse exposures …
human infants' development has mainly focused on the effects of early adverse exposures …
Increases in maternal depressive symptoms during pregnancy and infant cortisol reactivity: mediation by placental corticotropin-releasing hormone
Background: Maternal depressive symptoms in pregnancy may affect offspring health
through prenatal programming of the hypothalamic–pituitary–adrenal (HPA) axis. The …
through prenatal programming of the hypothalamic–pituitary–adrenal (HPA) axis. The …
Intergenerational transmission of emotion dysregulation: Part II. Developmental origins of newborn neurobehavior
We investigated whether neurobehavioral markers of risk for emotion dysregulation were
evident among newborns, as well as whether the identified markers were associated with …
evident among newborns, as well as whether the identified markers were associated with …
Impact of parental adverse childhood experiences on offspring development in early head start: Parental adversity and offspring development
A Miccoli, J Song, M Romanowicz… - Journal of primary …, 2022 - journals.sagepub.com
Adverse childhood experiences (ACEs) are potentially traumatic events that can cause
lifelong suffering, with 1 out of 2 children in the United States experiencing at least 1 ACEs …
lifelong suffering, with 1 out of 2 children in the United States experiencing at least 1 ACEs …