Recent advances in the molecular genetics of primary gliomas
GJ Kitange, KL Templeton… - Current opinion in …, 2003 - journals.lww.com
Primary brain tumors, particularly glioblastomas, remain a challenge for oncology.
Uncontrolled cellular proliferation, lack of apoptosis, invasion, and angiogenesis are among …
Uncontrolled cellular proliferation, lack of apoptosis, invasion, and angiogenesis are among …
Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas
Purpose High epidermal growth factor receptor (EGFR) gene copy number is associated
with poor prognosis in lung cancer, but such findings have not been reported for HNSCC. A …
with poor prognosis in lung cancer, but such findings have not been reported for HNSCC. A …
Immunohistochemical detection of EGFRvIII in high malignancy grade astrocytomas and evaluation of prognostic significance
The purpose of this study was to establish an accurate and accessible immunohistochemical
(IHC) method for detecting vIII Egf receptor and to assess the prognostic significance of the …
(IHC) method for detecting vIII Egf receptor and to assess the prognostic significance of the …
EGFR amplification and lack of activating mutations in metaplastic breast carcinomas
JS Reis‐Filho, C Pinheiro… - The Journal of …, 2006 - Wiley Online Library
Metaplastic breast carcinomas are reported to harbour epidermal growth factor receptor
(EGFR) overexpression in up to 80% of the cases, but EGFR gene amplification is the …
(EGFR) overexpression in up to 80% of the cases, but EGFR gene amplification is the …
The molecular epidemiology of gliomas in adults
In this paper the authors highlight recent findings from molecular epidemiology studies of
glioma origin and prognosis and suggest promising paths for future research. The reasons …
glioma origin and prognosis and suggest promising paths for future research. The reasons …
The expression of PAX6, PTEN, vascular endothelial growth factor, and epidermal growth factor receptor in gliomas: relationship to tumor grade and survival
Purpose: Malignant astrocytic gliomas, including anaplastic astrocytoma (AA) and
glioblastoma multiforme (GBM), result from various genetic perturbations and dysregulated …
glioblastoma multiforme (GBM), result from various genetic perturbations and dysregulated …
LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome
Enzyme-mediated damage repair or mitigation, while common for nucleic acids, is rare for
proteins. Examples of protein damage are elimination of phosphorylated Ser/Thr to …
proteins. Examples of protein damage are elimination of phosphorylated Ser/Thr to …
Functional genomic analysis identified epidermal growth factor receptor activation as the most common genetic event in oral squamous cell carcinoma
A 250K single-nucleotide polymorphism array was used to study subchromosomal
alterations in oral squamous cell carcinoma (OSCC). The most frequent amplification was …
alterations in oral squamous cell carcinoma (OSCC). The most frequent amplification was …
Reduced microRNA‐218 expression is associated with high nuclear factor kappa B activation in gastric cancer
C Gao, Z Zhang, W Liu, S Xiao, W Gu… - … International Journal of …, 2010 - Wiley Online Library
BACKGROUND: Poor expression of microRNAs (miRs) reportedly plays an important role in
gastric carcinogenesis. Large‐scale microarray assays have indicated that there is …
gastric carcinogenesis. Large‐scale microarray assays have indicated that there is …
[HTML][HTML] LANCL1 binds abscisic acid and stimulates glucose transport and mitochondrial respiration in muscle cells via the AMPK/PGC-1α/Sirt1 pathway
S Spinelli, G Begani, L Guida, M Magnone… - Molecular …, 2021 - Elsevier
Objective Abscisic acid (ABA) is a plant hormone also present and active in animals. In
mammals, ABA regulates blood glucose levels by stimulating insulin-independent glucose …
mammals, ABA regulates blood glucose levels by stimulating insulin-independent glucose …