Positive allosteric modulators of γ-aminobutyric acid-A (GABA A) receptors or GABAkines
have been widely used medicines for over 70 years for anxiety, epilepsy, sleep, and other …

Abstract γ-Aminobutyric acid (GABA) is the most prevalent inhibitory neurotransmitter in the
mammalian brain and has been found to play an important role in the pathogenesis or the …

Transmitters mediating'fast'synaptic processes in the vertebrate central nervous system are
commonly placed in two separate categories that are believed to exhibit no interaction at the …

The amino acid γ-aminobutyric-acid (GABA) prevails in the CNS as an inhibitory neurotrans-
mitter that mediates most of its effects through fast GABA-gated Cl−-channels (GABA AR) …

The construction of the brain relies on a series of well-defined genetically and experience-or
activity-dependent mechanisms which allow to adapt to the external environment. Disruption …

Investigation of the actions of the benzodiazepines has provided insights into the
neurochemical mechanisms underlying anxiety, seizures, muscle relaxation, and sedation …

Several neurotransmitters including noradrenaline (NA), gamma‐aminobutyric acid (GABA)
and serotonin (5‐HT), and also certain peptides, decrease the duration of the Na+‐Ca2+ …

The γ‐aminobutyric acid type A (GABAA) receptor represents an elementary switching
mechanism integral to the functioning of the central nervous system and a locus for the …

Several lines of evidence suggest that 17β-estradiol (βE2) has neuroprotective properties.
The risk and severity of dementia are decreased in women who have received estrogen …

Memory dysfunction is a symptomatic feature of many neurologic and neuropsychiatric
disorders; however, the basic underlying mechanisms of memory and altered states of …