The miR-200 family of microRNAs: fine tuners of epithelial-mesenchymal transition and circulating cancer biomarkers

I Cavallari, F Ciccarese, E Sharova, L Urso… - Cancers, 2021 - mdpi.com
Simple Summary MicroRNAs (miRNAs) are small RNA molecules that regulate gene
expression by blocking translation or inducing degradation of specific gene transcripts. The …

[HTML][HTML] Epigenetics in non-small cell lung cancer: from basics to therapeutics

J Ansari, RE Shackelford, H El-Osta - Translational lung cancer …, 2016 - ncbi.nlm.nih.gov
Lung cancer remains the number one cause of cancer-related deaths worldwide with
221,200 estimated new cases and 158,040 estimated deaths in 2015. Approximately 80% of …

Cell death pathways and viruses: role of microRNAs

JS Nahand, L Shojaie, SA Akhlagh… - … Therapy-Nucleic Acids, 2021 - cell.com
Viral infections lead to the death of more than a million people each year around the world,
both directly and indirectly. Viruses interfere with many cell functions, particularly critical …

miR-200c: a versatile watchdog in cancer progression, EMT, and drug resistance

M Mutlu, U Raza, Ö Saatci, E Eyüpoğlu… - Journal of Molecular …, 2016 - Springer
Abstract MicroRNAs (miRNAs) are 20–22-nucleotide small endogenous non-coding RNAs
which regulate gene expression at post-transcriptional level. In the last two decades …

Exosomal miR-141 promotes tumor angiogenesis via KLF12 in small cell lung cancer

S Mao, Z Lu, S Zheng, H Zhang, G Zhang… - Journal of Experimental …, 2020 - Springer
Background Angiogenesis, a basic requirement for tumor cell survival, is considered to be a
malignant characteristic of small cell lung cancer (SCLC) and is closely related to the poor …

Expression of serum miR-200a, miR-200b, and miR-200c as candidate biomarkers in epithelial ovarian cancer and their association with clinicopathological features

M Zuberi, R Mir, J Das, I Ahmad, J Javid… - Clinical and …, 2015 - Springer
Background MicroRNAs (miRs) have been implicated in the etiology of various human
cancers. The aim of this study was to investigate the association of the expression of three …

[HTML][HTML] Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer

J Tantai, D Hu, Y Yang, J Geng - International journal of clinical …, 2015 - ncbi.nlm.nih.gov
Objective: Long non-coding RNAs (lncRNAs) XIST and HIF1A-AS1 have been shown to play
important regulatory roles in cancer biology, and lncRNA-XIST and HIF1A-AS1 are …

Microarray profiling of circular RNAs in human papillary thyroid carcinoma

N Peng, L Shi, Q Zhang, Y Hu, N Wang, H Ye - PloS one, 2017 - journals.plos.org
Background Non-coding circular RNAs (circRNAs) have displayed dysregulated expression
in several human cancers. Here, we profiled the circRNA expression of papillary thyroid …

MiR-200 family and cancer: From a meta-analysis view

GL Huang, J Sun, Y Lu, Y Liu, H Cao, H Zhang… - Molecular Aspects of …, 2019 - Elsevier
The role of microRNAs (miRNAs) in cancer development was implicated as oncogene or
tumor suppressor. One of the miRNA family, the miR-200 family, was mainly characterized …

Combination of microRNA therapeutics with small-molecule anticancer drugs: mechanism of action and co-delivery nanocarriers

X Dai, C Tan - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNAs (miRNAs) regulate multiple molecular pathways vital for the hallmarks of cancer
with a high degree of biochemical specificity and potency. By restoring tumor suppressive …