Inside the diabetic brain: role of different players involved in cognitive decline

JM Gaspar, FI Baptista, MP Macedo… - ACS chemical …, 2016 - ACS Publications
Diabetes mellitus is the most common metabolic disease, and its prevalence is increasing. A
growing body of evidence, both in animal models and epidemiological studies, has …

Neuroprotection as a therapeutic target for diabetic retinopathy

C Hernández, M Dal Monte, R Simó… - Journal of diabetes …, 2016 - Wiley Online Library
Diabetic retinopathy (DR) is a multifactorial progressive disease of the retina and a leading
cause of vision loss. DR has long been regarded as a vascular disorder, although neuronal …

The effects of early diabetes on inner retinal neurons

ED Eggers, TA Carreon - Visual neuroscience, 2020 - cambridge.org
Diabetic retinopathy is now well understood as a neurovascular disease. Significant deficits
early in diabetes are found in the inner retina that consists of bipolar cells that receive inputs …

Visual dysfunction in diabetes

ED Eggers - Annual Review of Vision Science, 2023 - annualreviews.org
Although diabetic retinopathy (DR) is clinically diagnosed as a vascular disease, many
studies find retinal neuronal and visual dysfunction before the onset of vascular DR. This …

Associations between diabetic retinal microvasculopathy and neuronal degeneration assessed by swept-source OCT and OCT angiography

B Qiu, L Zhao, X Zhang, Y Wang, Q Wang, Y Nie… - Frontiers in …, 2021 - frontiersin.org
Purpose: To provide clinical evidence of the associations between retinal neuronal
degeneration and microvasculopathy in diabetic retinopathy (DR). Methods: This case …

[PDF][PDF] Treadmill training modifies KIF5B motor protein in the STZ-induced diabetic rat spinal cord and sciatic nerve

M Rahmati, R Gharakhanlou, M Movahedin… - Archives of Iranian …, 2015 - journalaim.com
BACKGROUND: Previous research has demonstrated diabetic-induced axonal transport
deficits. However, the mechanism of axonal transport impairment induced by diabetes is …

Diabetes alters KIF1A and KIF5B motor proteins in the hippocampus

FI Baptista, MJ Pinto, F Elvas, RD Almeida… - PloS one, 2013 - journals.plos.org
Diabetes mellitus is the most common metabolic disorder in humans. Diabetic
encephalopathy is characterized by cognitive and memory impairments, which have been …

[HTML][HTML] Diabetes changes expression of genes related to glutamate neurotransmission and transport in the Long-Evans rat retina

JCM Lau, RA Kroes, JR Moskal… - Molecular vision, 2013 - ncbi.nlm.nih.gov
Purpose This study investigated changes in the transcript levels of genes related to
glutamate neurotransmission and transport as diabetes progresses in the Long-Evans rat …

Hormonal signaling systems of the brain in diabetes mellitus

A Shpakov, O Chistyakova, K Derkach… - Neurodegenerative …, 2011 - books.google.com
Diabetes mellitus (DM) is nowadays a major global health problem affecting more than 200
million people worldwide. It is one of the most severe metabolic disorders in humans …

Alterations of the glutamatergic system in diabetes mellitus

M Hristov, A Nankova, P Andreeva-Gateva - Metabolic Brain Disease, 2024 - Springer
Diabetes mellitus (DM) is a chronic disease characterized by elevated blood glucose levels
caused by a lack of insulin production (type 1 diabetes) or insulin resistance (type 2 …