A variational algorithm to detect the clonal copy number substructure of tumors from scRNA-seq data
Single-cell RNA sequencing is the reference technology to characterize the composition of
the tumor microenvironment and to study tumor heterogeneity at high resolution. Here we …
the tumor microenvironment and to study tumor heterogeneity at high resolution. Here we …
The use of genetics for reaching a diagnosis in XY DSD
Reaching a firm diagnosis is vital for the long-term management of a patient with a
difference or disorder of sex development (DSD). This is especially the case in XY DSD …
difference or disorder of sex development (DSD). This is especially the case in XY DSD …
Comprehensive genomic profiling of patient-matched head and neck cancer cells: a preclinical pipeline for metastatic and recurrent disease
L Nisa, D Barras, M Medová, DM Aebersold… - Molecular cancer …, 2018 - AACR
Metastases and tumor recurrence have a major prognostic impact in head and neck
squamous cell carcinoma (HNSCC); however, cellular models that comprehensively …
squamous cell carcinoma (HNSCC); however, cellular models that comprehensively …
運用高通量全外顯子定序偵測複製數變異工具之評估與整合
李正揚 - 臺北醫學大學醫學資訊研究所學位論文, 2016 - airitilibrary.com
複製數變異(Copy Number Variations, CNVs) 是一種其長度定義為大於50 核苷酸, 且在DNA
序列上發生多重複製(Amplifications), 刪除(Deletions), 易位(Translocations), 嵌入(Insertions) …
序列上發生多重複製(Amplifications), 刪除(Deletions), 易位(Translocations), 嵌入(Insertions) …
[PDF][PDF] ANTI-CANCER PROPERTIES OF TAT-RasGAP317_326 AND MOLECULAR MECHANISMS OF RESISTANCE TO SORAFENIB
N Chevalier - 2017 - serval.unil.ch
Although some types of tumours are now considered curable, cancer remains one of the
deadliest diseases in the world. While various therapeutic strategies exist to treat malignant …
deadliest diseases in the world. While various therapeutic strategies exist to treat malignant …