Autophagy is an explicit cellular process to deliver dissimilar cytoplasmic misfolded proteins,
lipids and damaged organelles to the lysosomes for degradation and elimination. The …

Abstract Glycogen synthase kinase-3 (GSK-3) is a protein kinase that can phosphorylate
over a hundred substrates and regulate cell differentiation, proliferation, and death …

During the last years, the role of astro-and microglial cells and associated
neuroinflammation in the pathogenesis of epilepsy has been extensively discussed. These …

Decreased ATPergic signaling is an increasingly recognized pathophysiology in bipolar
mania disease models. In parallel, adenosine deficit is increasingly recognized in epilepsy …

Seizures are a concerning adverse event frequently associated with the use of psychedelics,
and hence, studies involving these substances tend to exclude patients with past history of …

The lithium-pilocarpine model is commonly used to recapitulate characteristics of human
intractable focal epilepsy. In the current study, we explored the impact of topiramate (TPM) …

Lithium is one of the lightest elements on Earth and it has been in the environment since the
formation of the galaxy. While a common element, it has not been found to be an essential …

Objective: To assess the effect of sericin against pentylenetetrazole (PTZ) kindling epilepsy
and its associated comorbidities. Methods: Epilepsy was induced with PTZ at the dose of 30 …

Children with autism spectrum disorder (ASD) may exhibit metabolic abnormalities, either
with or without an underlying inherited metabolic disorder. Some of these metabolic …

Psychiatric presentations in older adults are complicated by chronic comorbidities,
polypharmacy, and older age-related psychosocial changes. This case report discusses an …