Animal models refers to the animal experimental objects and related materials that can
simulate human body established in medical research. As the second-largest disease in …

Functional annotation of genomes is a prerequisite for contemporary basic and applied
genomic research, yet farmed animal genomics is deficient in such annotation. To address …

Simple Summary The intramuscular fat (IMF) or marbling is an essential pork sensory quality
that influences the preference of the consumers and premiums for pork. IMF is the streak of …

Despite an improved understanding of cancer molecular biology, immune landscapes, and
advancements in cytotoxic, biologic, and immunologic anti-cancer therapeutics, cancer …

Perinatal hypoxia-ischemia resulting in death or lifelong disabilities remains a major clinical
disorder. Neonatal models of hypoxia-ischemia in rodents have enhanced our …

DNA-methylation profiles have been used successfully to develop highly accurate
biomarkers of age, epigenetic clocks, for many species. Using a custom methylation array …

Background Efforts to improve animal health, and understand genetic bases for production,
may benefit from a comprehensive analysis of animal genomes and epigenomes. Although …

Background Although sperm DNA methylation has been studied in humans and other
species, its status in cattle is largely unknown. Results Using whole-genome bisulfite …

Enhanced understanding of the molecular features of glioma has led to an expansion of
murine glioma models and successful preclinical studies. However, clinical trials continue to …

The immune system plays dual roles in response to cancer. The host immune system
protects against tumor formation via immunosurveillance; however, recognition of the tumor …