Domains in Action: Understanding Ddi1's Diverse Functions in the Ubiquitin-Proteasome System
A Fabijan, B Polis, A Zawadzka-Fabijan… - International Journal of …, 2024 - mdpi.com
The ubiquitin-proteasome system (UPS) is a pivotal cellular mechanism responsible for the
selective degradation of proteins, playing an essential role in proteostasis, protein quality …
selective degradation of proteins, playing an essential role in proteostasis, protein quality …
[HTML][HTML] Variant-to-function mapping of late-onset Alzheimer's disease GWAS signals in human microglial cell models implicates RTFDC1 at the CASS4 locus
EA Burton, M Argenziano, K Cook, M Ridler, S Lu… - …, 2024 - pmc.ncbi.nlm.nih.gov
Late-onset Alzheimer's disease (LOAD) research has principally focused on neurons over
the years due to their known role in the production of amyloid beta plaques and …
the years due to their known role in the production of amyloid beta plaques and …