Polymeric nanoparticles for drug delivery in glioblastoma: State of the art and future perspectives
Glioblastoma (GBM) is an aggressive, fatal and malignant primary brain tumor. Despite the
current standard treatment for glioblastoma patients including neurosurgical resection …
current standard treatment for glioblastoma patients including neurosurgical resection …
Folate receptors' expression in gliomas may possess potential nanoparticle-based drug delivery opportunities
Brain cancer effected around estimated 23 890 adults and 3540 children under the age of
15 in 2020. The chemotherapeutic agents that are already approved by the FDA for brain …
15 in 2020. The chemotherapeutic agents that are already approved by the FDA for brain …
Combination of vitamin C and curcumin safeguards against methotrexate-induced acute liver injury in mice by synergistic antioxidant effects
D Hasan Khudhair, AI Al-Gareeb… - Frontiers in …, 2022 - frontiersin.org
Methotrexate (MTX), an antineoplastic and immunosuppressive drug, widely used in the
treatment of different types of cancers and the management of chronic inflammatory …
treatment of different types of cancers and the management of chronic inflammatory …
Paclitaxel/methotrexate co-loaded PLGA nanoparticles in glioblastoma treatment: Formulation development and in vitro antitumor activity evaluation
Aim The aim of this study was to improve the therapeutic index of chemotherapeutic drugs
on glioblastoma cells through an improved co-drug delivery system. Materials and methods …
on glioblastoma cells through an improved co-drug delivery system. Materials and methods …
Anticancer evaluation of methotrexate and curcumin-coencapsulated niosomes against colorectal cancer cell lines
Aim: The aim of the present investigation was to develop niosomes containing both
curcumin (CUR) and methotrexate (MTX). Also, the combinational effect of CUR and MTX in …
curcumin (CUR) and methotrexate (MTX). Also, the combinational effect of CUR and MTX in …
Effect of Paclitaxel/etoposide co-loaded polymeric nanoparticles on tumor size and survival rate in a rat model of glioblastoma
H Maleki, MRH Najafabadi, TJ Webster… - International journal of …, 2021 - Elsevier
The aim of this work is to co-load paclitaxel (PTX) and etoposide (ETP) in methoxy poly
(ethylene glycol)-poly (lactic-co-glycolic acid) nanoparticles (mPEG-PLGA NPs) to overcome …
(ethylene glycol)-poly (lactic-co-glycolic acid) nanoparticles (mPEG-PLGA NPs) to overcome …
Phytochemical add-on therapy to DMARDs therapy in rheumatoid arthritis: In vitro and in vivo bases, clinical evidence and future trends
The use of biologically active compounds derived from plants ie phytochemicals, have been
known for ages for their pharmacological activities in the treatment of autoimmune disorders …
known for ages for their pharmacological activities in the treatment of autoimmune disorders …
Design of carbon and graphene quantum dots based nanotheranostics applications for glioblastoma management: Recent advanced and future prospects
S Nangare, S Chandankar, P Patil - Journal of Drug Delivery Science and …, 2023 - Elsevier
The primary challenges in combating Glioblastoma multiforme (GBM) include the lack of
early detection methods and precision therapies. In response to this pressing need, this …
early detection methods and precision therapies. In response to this pressing need, this …
Fabrication, optimization, and evaluation of paclitaxel and curcumin coloaded PLGA nanoparticles for improved antitumor activity
H Hu, Z Liao, M Xu, S Wan, Y Wu, W Zou, J Wu… - ACS …, 2022 - ACS Publications
Codelivery of chemotherapeutic drugs in nanoparticles can enhance the therapeutic effects
against tumors. However, their anticancer properties and physiochemical characteristics can …
against tumors. However, their anticancer properties and physiochemical characteristics can …
Review on the therapeutic potential of curcumin and its derivatives on glioma biology
M Mohamadian, SS Ahmadi, A Bahrami… - Neurochemical …, 2022 - Springer
Gliomas are common and aggressive brain tumors that carry a poor prognosis. The current
multimodal therapeutic option for glioma includes surgery subsequently temozolomide …
multimodal therapeutic option for glioma includes surgery subsequently temozolomide …