De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences

N Vakirlis, O Acar, B Hsu, N Castilho Coelho… - Nature …, 2020 - nature.com
Recent evidence demonstrates that novel protein-coding genes can arise de novo from non-
genic loci. This evolutionary innovation is thought to be facilitated by the pervasive …

Intergenic regions of Saccharomycotina yeasts are enriched in potential to encode transmembrane domains

E Tassios, C Nikolaou, N Vakirlis - Molecular Biology and …, 2023 - academic.oup.com
Intergenic genomic regions have essential regulatory and structural roles that impose
constraints on their sequences. But regions that do not currently encode proteins also carry …

Intergenic regions of Saccharomycotina yeasts are enriched in potential to form transmembrane domains

E Tassios, C Nikolaou, N Vakirlis - bioRxiv, 2022 - biorxiv.org
Intergenic genomic regions have essential regulatory and structural roles that impose
constraints on their sequences. But regions that do not currently encode proteins, also carry …

De novo emergence of adaptive membrane proteins from thymine-rich intergenic sequences

N Vakirlis, O Acar, B Hsu, NC Coelho, SB Van Oss… - bioRxiv, 2019 - biorxiv.org
Recent evidence demonstrates that novel protein-coding genes can arise de novo from
intergenic loci. This evolutionary innovation is thought to be facilitated by the pervasive …