Heavy metals are well-known environmental pollutants owing to their toxicity, longevity in
the atmosphere, and ability to accumulate in the human body via bioaccumulation. The …

Metals serve important roles in the human body, including the maintenance of cell structure
and the regulation of gene expression, the antioxidant response, and neurotransmission …

Currently prescribed medications for the treatment of Alzheimer's disease (AD) that are
based on acetylcholinesterase inhibition only offer symptomatic relief but do not provide …

NLRP3 inflammasome mediated pyroptosis is involved in cadmium exposure-induced
neuroinflammation through the IL-1β/IkB-α-NF-κB-NLRP3 feedback loop in swine …

The present work aims to evaluate the effect of melatonin (Mel) on affective and cognitive
disorders induced by chronic exposure to Cadmium (Cd). Male and female Wistar rats …

Cadmium (Cd), a ubiquitous environmental pollutant, has neurotoxicity to humans and
animals. Quercetin (QE), the main component of flavonoids, has strong antioxidant and anti …

Walnut peptide, a low molecular weight peptide separated from walnuts by enzymatic
hydrolysis, is considered as a potential nutraceutical with a variety of biological activities. In …

Depression is a serious public health problem today, especially in middle-aged and older
adults. Although the etiology of the disease has not been fully elucidated, environmental …

Cadmium (Cd) as a ubiquitous toxic heavy metal is reported to affect the nervous system.
Selenium (Se) has been shown to have antagonistic effects against heavy metal toxicity. In …

Background Exposure to low-dose toxic metals in the environment is ubiquitous. Several
murine studies have shown metals induce anxiety-like behaviors, and mechanistic research …