Glutamate and dopamine in schizophrenia: An update for the 21st century

O Howes, R McCutcheon… - Journal of …, 2015 - journals.sagepub.com
The glutamate and dopamine hypotheses are leading theories of the pathoaetiology of
schizophrenia. Both were initially based on indirect evidence from pharmacological studies …

Dopamine receptors–IUPHAR R eview 13

JM Beaulieu, S Espinoza… - British journal of …, 2015 - Wiley Online Library
The variety of physiological functions controlled by dopamine in the brain and periphery is
mediated by the D 1, D 2, D 3, D 4 and D 5 dopamine GPCRs. Drugs acting on dopamine …

The physiology, signaling, and pharmacology of dopamine receptors

JM Beaulieu, RR Gainetdinov - Pharmacological reviews, 2011 - ASPET
G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the
physiological functions of the catecholaminergic neurotransmitter dopamine, ranging from …

Where is dopamine and how do immune cells see it?: dopamine-mediated immune cell function in health and disease

SM Matt, PJ Gaskill - Journal of Neuroimmune Pharmacology, 2020 - Springer
Dopamine is well recognized as a neurotransmitter in the brain, and regulates critical
functions in a variety of peripheral systems. Growing research has also shown that …

[HTML][HTML] Lateral hypothalamus, nucleus accumbens, and ventral pallidum roles in eating and hunger: interactions between homeostatic and reward circuitry

DC Castro, SL Cole, KC Berridge - Frontiers in systems neuroscience, 2015 - frontiersin.org
The study of the neural bases of eating behavior, hunger, and reward has consistently
implicated the lateral hypothalamus (LH) and its interactions with mesocorticolimbic circuitry …

[HTML][HTML] Basal Ganglia disorders associated with imbalances in the striatal striosome and matrix compartments

JR Crittenden, AM Graybiel - Frontiers in neuroanatomy, 2011 - frontiersin.org
The striatum is composed principally of GABAergic, medium spiny striatal projection neurons
(MSNs) that can be categorized based on their gene expression, electrophysiological …

[HTML][HTML] Striatal Neurons Expressing D1 and D2 Receptors are Morphologically Distinct and Differently Affected by Dopamine Denervation in Mice

D Gagnon, S Petryszyn, MG Sanchez, C Bories… - Scientific reports, 2017 - nature.com
The loss of nigrostriatal dopamine neurons in Parkinson's disease induces a reduction in the
number of dendritic spines on medium spiny neurons (MSNs) of the striatum expressing D1 …

[HTML][HTML] Sex differences in dopamine receptors and relevance to neuropsychiatric disorders

OOF Williams, M Coppolino, SR George, ML Perreault - Brain sciences, 2021 - mdpi.com
Dopamine is an important neurotransmitter that plays a key role in neuropsychiatric illness.
Sex differences in dopaminergic signaling have been acknowledged for decades and have …

[HTML][HTML] Separate GABA afferents to dopamine neurons mediate acute action of opioids, development of tolerance, and expression of withdrawal

A Matsui, BC Jarvie, BG Robinson, ST Hentges… - Neuron, 2014 - cell.com
GABA release from interneurons in VTA, projections from the nucleus accumbens (NAc),
and rostromedial tegmental nucleus (RMTg) was selectively activated in rat brain slices. The …

Reappraising striatal D1-and D2-neurons in reward and aversion

C Soares-Cunha, B Coimbra, N Sousa… - … & Biobehavioral Reviews, 2016 - Elsevier
The striatum has been involved in complex behaviors such as motor control, learning,
decision-making, reward and aversion. The striatum is mainly composed of medium spiny …