Mechanisms and biomarkers of cancer-associated thrombosis

AS Kim, AA Khorana, KR McCrae - Translational Research, 2020 - Elsevier
Cancer-associated thrombosis is a leading cause of non-cancer death in cancer patients
and is comprised of both arterial and venous thromboembolism (VTE). There are multiple …

PAD4 and its inhibitors in cancer progression and prognosis

D Zhu, Y Lu, Y Wang, Y Wang - Pharmaceutics, 2022 - mdpi.com
The systemic spread of malignancies and the risk of cancer-associated thrombosis are
major clinical challenges in cancer therapy worldwide. As an important post-translational …

[HTML][HTML] Согласованное мнение российских экспертов по профилактике, диагностике и лечению сердечно-сосудистой токсичности противоопухолевой …

ЮА Васюк, ГЕ Гендлин, ЕИ Емелина… - Российский …, 2021 - cyberleninka.ru
АВ—атриовентрикулярный (ая) АГ—артериальная гипертензия АД—артериальное
давление АТ—артериальный тромбоз АТО—атеротромботические осложнения АТФ …

Distinct clinico-molecular arterial and venous thrombosis scores for myeloproliferative neoplasms risk stratification

H Pasquer, R Daltro de Oliveira, L Vasseur… - Leukemia, 2024 - nature.com
Current recommended risk scores to predict thrombotic events associated with
myeloproliferative neoplasms (MPN) do not discriminate between arterial and venous …

Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-β

A Metelli, BX Wu, B Riesenberg, S Guglietta… - Science translational …, 2020 - science.org
Cancer-associated thrombocytosis and high concentrations of circulating transforming
growth factor–β1 (TGF-β1) are frequently observed in patients with progressive cancers …

Impact of neutrophil extracellular traps on thrombosis formation: New findings and future perspective

Y Zhou, Z Xu, Z Liu - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
Thrombotic diseases seriously endanger human health, neutrophils and neutrophil
extracellular traps (NETs) play an important role in abnormal thrombus formation. NETs are …

Platelet-cancer interplay: molecular mechanisms and new therapeutic avenues

A Braun, HJ Anders, T Gudermann… - Frontiers in …, 2021 - frontiersin.org
Although platelets are critically involved in thrombosis and hemostasis, experimental and
clinical evidence indicate that platelets promote tumor progression and metastasis through a …

Relation of mean platelet volume (MPV) with cancer: a systematic review with a focus on disease outcome on twelve types of cancer

P Detopoulou, GI Panoutsopoulos, M Mantoglou… - Current …, 2023 - mdpi.com
Inflammatory proteins activate platelets, which have been observed to be directly related to
cancer progression and development. The aim of this systematic review is to investigate the …

The role of coagulome in the tumor immune microenvironment

R Wahab, MM Hasan, Z Azam, PJ Grippo… - Advanced drug delivery …, 2023 - Elsevier
The rising incidence and persistent thrombosis in multiple cancers including those that are
immunosuppressive highlight the need for understanding the tumor coagulome system and …

The D-dimer level predicts the prognosis in patients with lung cancer: a systematic review and meta-analysis

M Ma, R Cao, W Wang, B Wang, Y Yang… - Journal of …, 2021 - Springer
Objective Although the significance of increased plasma D-dimer levels in activating
coagulation and fibrinolysis has been reported, it is still controversial whether it can be used …