[HTML][HTML] Neurofilament proteins as biomarkers to monitor neurological diseases and the efficacy of therapies
Biomarkers of neurodegeneration and neuronal injury have the potential to improve
diagnostic accuracy, disease monitoring, prognosis, and measure treatment efficacy …
diagnostic accuracy, disease monitoring, prognosis, and measure treatment efficacy …
The potential of blood neurofilament light as a marker of neurodegeneration for Alzheimer's disease
Y Jung, JS Damoiseaux - Brain, 2024 - academic.oup.com
Over the past several years, there has been a surge in blood biomarker studies examining
the value of plasma or serum neurofilament light (NfL) as a biomarker of neurodegeneration …
the value of plasma or serum neurofilament light (NfL) as a biomarker of neurodegeneration …
[HTML][HTML] The inflammasome adaptor protein ASC in mild cognitive impairment and Alzheimer's disease
XO Scott, ME Stephens, MC Desir, WD Dietrich… - International journal of …, 2020 - mdpi.com
Mild cognitive impairment (MCI) is characterized by memory loss in the absence of dementia
and is considered the translational stage between normal aging and early Alzheimer's …
and is considered the translational stage between normal aging and early Alzheimer's …
Association of plasma neurofilament light with small vessel disease burden in nondemented elderly: a longitudinal study
Y Qu, CC Tan, XN Shen, HQ Li, M Cui, L Tan, Q Dong… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Neurofilament light chain (NfL) is a promising predictive
biomarker of active axonal injury and neuronal degeneration diseases. We aimed to …
biomarker of active axonal injury and neuronal degeneration diseases. We aimed to …
[HTML][HTML] Plasma NfL is associated with the APOE ε4 allele, brain imaging measurements of neurodegeneration, and lower recall memory scores in cognitively …
Abstract Background Plasma neurofilament light (NfL) is an indicator of neurodegeneration
and/or neuroaxonal injury in persons with Alzheimer's disease (AD) and a wide range of …
and/or neuroaxonal injury in persons with Alzheimer's disease (AD) and a wide range of …
Different clinical contexts of use of blood neurofilament light chain protein in the spectrum of neurodegenerative diseases
G Palermo, S Mazzucchi, A Della Vecchia… - Molecular …, 2020 - Springer
One of the most pressing challenges in the clinical research of neurodegenerative diseases
(NDDs) is the validation and standardization of pathophysiological biomarkers for different …
(NDDs) is the validation and standardization of pathophysiological biomarkers for different …
Association of serum biomarker neurofilament light concentration with post-stroke depression: a preliminary study
H Zhao, M Mo, C Miao, L Li, H Yang, Y Liu… - General hospital …, 2020 - Elsevier
Objective To investigate serum neurofilament light (sNfL) levels in acute ischemic stroke and
to assess whether sNfL are related to the severity of disease and a potential prognostic …
to assess whether sNfL are related to the severity of disease and a potential prognostic …
The potential of neurofilament light as a biomarker in Alzheimer's disease
Y Xiong, T Meng, J Luo, H Zhang - European neurology, 2021 - karger.com
Background: Alzheimer's disease (AD) is the most common neurodegenerative disease
characterized by progressive memory loss and cognitive impairment. In 2011, the National …
characterized by progressive memory loss and cognitive impairment. In 2011, the National …
A systematic review of the association between amyloid-β and τ pathology with functional connectivity alterations in the Alzheimer dementia spectrum utilizing PET …
The association between functional connectivity (FC) alterations with amyloid-β (Aβ) and τ
protein depositions in Alzheimer dementia is a subject of debate in the current literature …
protein depositions in Alzheimer dementia is a subject of debate in the current literature …
[HTML][HTML] Plasma neurofilament light chain: a biomarker predicting severity in patients with acute ischemic stroke
J Wu, D Wu, Y Liang, Z Zhang, L Zhuang, Z Wang - Medicine, 2022 - journals.lww.com
Neurofilament light chain (NfL) levels have proved to be a good biomarker in cerebrospinal
fluid (CSF) correlating with the degree of neuronal injury and neurodegeneration. However …
fluid (CSF) correlating with the degree of neuronal injury and neurodegeneration. However …