Circadian clocks organize behavior and physiology to adapt to daily environmental cycles.
Genetic approaches in the fruit fly, Drosophila melanogaster, have revealed widely …

Cryptochromes (CRYs) are flavoproteins that are sensitive to blue light, first identified in
Arabidopsis and then in Drosophila and mice. They are evolutionarily conserved and play …

Background Daily behaviors in animals are determined by the interplay between internal
timing signals from circadian clocks and environmental stimuli such as light. How these …

Seven neuropeptides are expressed within the Drosophila brain circadian network. Our
previous mRNA profiling suggested that Allatostatin-C (AstC) is an eighth neuropeptide and …

Behavioral responsiveness to external stimulation is shaped by context. We studied how
sensory information can be contextualized, by examining light-evoked locomotor …

The fruit fly, Drosophila melanogaster, is generally diurnal, but a few mutant strains, such as
the circadian clock mutant ClkJrk, have been described as nocturnal. We report here that …

Metabolism influences locomotor behaviors, but the understanding of neural curcuit control
for that is limited. Under standard light-dark cycles, Drosophila exhibits bimodal morning (M) …

Sleep-like states have been described in Drosophila and the mechanisms and factors that
generate and define sleep-wake profiles in this model organism are being thoroughly …

Drosophila circadian behavior relies on the network of heterogeneous groups of clock
neurons. Short-and long-range signaling within the pacemaker circuit coordinates molecular …

Sleep is a highly conserved behavior whose role is as yet unknown, although it is widely
acknowledged as being important. Here we provide an overview of many vital questions …