[HTML][HTML] Current knowledge on exosome biogenesis, cargo-sorting mechanism and therapeutic implications

S Xie, Q Zhang, L Jiang - Membranes, 2022 - mdpi.com
Extracellular vesicles (EVs) are nanoscale membrane vesicles released by donor cells that
can be taken up by recipient cells. The study of EVs has the potential to identify unknown …

[HTML][HTML] Exosomal circRNAs: biogenesis, effect and application in human diseases

Y Wang, J Liu, J Ma, T Sun, Q Zhou, W Wang, G Wang… - Molecular cancer, 2019 - Springer
Exosomes have emerged as critical mediators of intercellular communication, both locally
and systemically, by regulating a diverse range of biological processes between cells …

[HTML][HTML] Guidelines for clinical translation and commercialization of extracellular vesicles and exosomes based therapeutics

K Cheng, R Kalluri - Extracellular Vesicle, 2023 - Elsevier
Extracellular vesicles (EVs) are lipid-bilayer delimited membrane structures released by
cells, and play a role in intercell communication and disease development. The Global …

[HTML][HTML] The crosstalk: Exosomes and lipid metabolism

W Wang, N Zhu, T Yan, YN Shi, J Chen… - Cell Communication and …, 2020 - Springer
Exosomes have been considered as novel and potent vehicles of intercellular
communication, instead of “cell dust”. Exosomes are consistent with anucleate cells, and …

[HTML][HTML] Exosomal transfer of long non-coding RNA SBF2-AS1 enhances chemoresistance to temozolomide in glioblastoma

Z Zhang, J Yin, C Lu, Y Wei, A Zeng, Y You - Journal of Experimental & …, 2019 - Springer
Background Acquired drug resistance is a constraining factor in clinical treatment of
glioblastoma (GBM). However, the mechanisms of chemoresponsive tumors acquire …

[HTML][HTML] Melanoma-derived exosomal miR-125b-5p educates tumor associated macrophages (TAMs) by targeting lysosomal acid lipase A (LIPA)

D Gerloff, J Lützkendorf, RKC Moritz, T Wersig… - Cancers, 2020 - mdpi.com
Tumor-associated macrophages (TAMs) are the most abundant immune cells in the tumor
microenvironment, promoting tumor initiation, growth, progression, metastasis, and immune …

In vitro wound healing activity of wheat-derived nanovesicles

F Şahin, P Koçak, MY Güneş, İ Özkan, E Yıldırım… - Applied biochemistry …, 2019 - Springer
Triticum aestivum plant extracts are often used as a natural healer in traditional medicine but
which particles mainly have role in these processes are not scientifically proven. In other …

IGF2BP1 regulates the cargo of extracellular vesicles and promotes neuroblastoma metastasis

MR Dhamdhere, CP Gowda, V Singh, Z Liu… - Oncogene, 2023 - nature.com
Neuroblastoma is a highly metastatic cancer, and thus is one of the leading causes of
cancer-related mortalities in pediatric patients. More than 50% of NB cases exhibit 17q21-ter …

Exosomes in lung cancer diagnosis and treatment. From the translating research into future clinical practice

C Masaoutis, C Mihailidou, G Tsourouflis, S Theocharis - Biochimie, 2018 - Elsevier
Lung cancer is one of the main causes of cancer-related death worldwide. Despite
advances in lung cancer pathophysiology, diagnosis and prognosis, a better understanding …

[HTML][HTML] Extracellular vesicles biogenesis, isolation, manipulation and genetic engineering for potential in vitro and in vivo therapeutics: An overview

N Hadizadeh, D Bagheri, M Shamsara… - … in Bioengineering and …, 2022 - frontiersin.org
The main goals of medicine consist of early detection and effective treatment of different
diseases. In this regard, the rise of exosomes as carriers of natural biomarkers has recently …