Neisseria meningitidis (the meningococcus) causes significant morbidity and mortality in
children and young adults worldwide through epidemic or sporadic meningitis and/or …

Multilocus sequence typing (MLST) was proposed in 1998 as a portable, universal, and
definitive method for characterizing bacteria, using the human pathogen Neisseria …

Meningococcal disease occurs worldwide with incidence rates varying from 1 to 1000 cases
per 100,000. The causative organism, Neisseria meningitidis, is an obligate commensal of …

Background. In 1999, meningococcal serogroup C conjugate (MCC) vaccines were
introduced in the United Kingdom for those under 19 years of age. The impact of this …

Meningococcal disease remains an important cause of morbidity and death worldwide
despite the development and increasing implementation of effective vaccines. Elimination of …

The human species is the only natural host of Neisseria meningitidis, an important cause of
bacterial meningitis globally, and, despite its association with devastating diseases, N …

Since the first outbreaks of meningococcal meningitis were first described in Geneva in 1804
and in New England in 1806, and since the discovery of the causative agent by in 1887 and …

Neisseria meningitidis, an obligate commensal of humans, normally colonizes the mucosa
of the upper respiratory tract without affecting the host, a phenomenon known as carriage. In …

Abstract Background Recombinant forms of Neisseria meningitidis human factor H binding
protein (fHBP) are undergoing clinical trials in candidate vaccines against invasive …

Host defence against microbial pathogens requires appropriate coordination of multiple
signalling pathways. These pathways are triggered by innate immune recognition of …