Fertility loss: negative effects of environmental toxicants on oogenesis

X Yao, W Liu, Y Xie, M Xi, L Xiao - Frontiers in Physiology, 2023 - frontiersin.org
There has been a global decline in fertility rates, with ovulatory disorders emerging as the
leading cause, contributing to a global lifetime infertility prevalence of 17.5%. Formation of …

Perfluorooctanoic acid (PFOA) inhibits steroidogenesis and mitochondrial function in bovine granulosa cells in vitro

R Kabakci, KL Clark, MR Plewes, CF Monaco… - Environmental …, 2023 - Elsevier
Perfluorooctanoic acid (PFOA) is a persistent environmental contaminant. Due to the
ubiquitous presence of PFOA in the environment, the impacts of PFOA exposure not only …

Assessment of toxicity potential of neglected Mithi River water from Mumbai megacity, India, in zebrafish using embryotoxicity, teratogenicity, and genotoxicity …

M Harshavarthini, MA Pathan, N Poojary… - Environmental …, 2023 - Springer
Abstract The Mithi River begins at Vihar Lake and flows through the industrial hub of the city
of Mumbai, India, and merges with the Arabian Sea at Mahim Creek. The current study was …

Effects of perfluorooctanoic acid in oxidative stress generation, DNA damage in cumulus cells, and its impact on in vitro maturation of porcine oocytes

T Mario, D Yvonne, S Veronica… - Environmental …, 2022 - Wiley Online Library
Perfluorooctanoic acid is a synthetic compound mostly used in a wide range of consumer
products with several adverse effects on somatic cells and gametes. It has been linked to …

Monosaccharide Composition and In Vitro Activity to HCT-116 Cells of Purslane Polysaccharides after a Covalent Chemical Selenylation

LY Li, QY Guan, YR Lin, JR Zhao, L Wang, Q Zhang… - Foods, 2022 - mdpi.com
The anti-cancer effects of selenylated plant polysaccharides are a focus of research. As a
natural plant with extensive biological effects, there have been few studies related to edible …

[HTML][HTML] Bovine oocyte exposure to perfluorohexane sulfonate (PFHxS) induces phenotypic, transcriptomic, and DNA methylation changes in resulting embryos in vitro

I Hallberg, S Persson, M Olovsson, M Moberg… - Reproductive …, 2022 - Elsevier
Abstract Knowledge on the effects of perfluorohexane sulfonate (PFHxS) on ovarian function
is limited. In the current study, we investigated the sensitivity of oocytes to PFHxS during in …

[PDF][PDF] Changes in nucleus and cytoplast during oocyte maturation: Involvement in embryo production

R Al-Zeidi, H Al Masruri, A Al Mufarji… - Adv. Anim. Vet …, 2022 - researchgate.net
Embryo production steps either in vivoor in vitroinclude oocyte meiotic maturation,
fertilization and culture processes. Oocyte maturation is the first step for in vivo or in vitro …

Perfluorooctanoic acid inhibits the maturation rate of mouse oocytes cultured in vitro by triggering mitochondrial and DNA damage

C Guo, Z Zhao, K Zhao, J Huang, L Ding… - Birth Defects …, 2021 - Wiley Online Library
Background Perfluorooctanoic acid (PFOA) is widely used in the manufacture of household
and industrial products. It has certain toxicity and leaves many residues in the environment …

Occurrence of late-apoptotic symptoms in porcine preimplantation embryos upon exposure of oocytes to perfluoroalkyl substances (PFASs) under in vitro meiotic …

A Leclercq, P Ranefall, YCB Sjunnesson, I Hallberg - Plos one, 2022 - journals.plos.org
The objectives of this study were to evaluate the effect of perfluoroalkyl substances on early
embryonic development and apoptosis in blastocysts using a porcine in vitro model. Porcine …

[PDF][PDF] Role of cumulus cells and follicular fluid on oocyte maturation and developmental competence of embryos: Intact and reconstructed oocytes

R Al Zeidi, H Al Masruri, A Al Mufarji… - Adv. Anim. Vet …, 2022 - researchgate.net
Ovarian follicles develop during fetal and postnatal periods through several distinct phases
and they release their matured ova upon puberty. Oocytes surrounded by a single layer of …