[HTML][HTML] Pharmaceutical dispersion techniques for dissolution and bioavailability enhancement of poorly water-soluble drugs
X Zhang, H Xing, Y Zhao, Z Ma - Pharmaceutics, 2018 - mdpi.com
Over the past decades, a large number of drugs as well as drug candidates with poor
dissolution characteristics have been witnessed, which invokes great interest in enabling …
dissolution characteristics have been witnessed, which invokes great interest in enabling …
[HTML][HTML] Application of flash nanoprecipitation to fabricate poorly water-soluble drug nanoparticles
Nanoparticles are considered to be a powerful approach for the delivery of poorly water-
soluble drugs. One of the main challenges is developing an appropriate method for …
soluble drugs. One of the main challenges is developing an appropriate method for …
3D printed orodispersible films with Aripiprazole
W Jamróz, M Kurek, E Łyszczarz, J Szafraniec… - International journal of …, 2017 - Elsevier
Three dimensional printing technology is gaining in importance because of its increasing
availability and wide applications. One of the three dimensional printing techniques is Fused …
availability and wide applications. One of the three dimensional printing techniques is Fused …
Drug nanocrystals: Fabrication methods and promising therapeutic applications
IS Mohammad, H Hu, L Yin, W He - International journal of pharmaceutics, 2019 - Elsevier
The drug nanocrystals (NCs) with unique physicochemical properties are now considered
as a promising drug delivery system for poorly water-soluble drugs. So far> 20 formulations …
as a promising drug delivery system for poorly water-soluble drugs. So far> 20 formulations …
[HTML][HTML] Injected nanocrystals for targeted drug delivery
Nanocrystals are pure drug crystals with sizes in the nanometer range. Due to the
advantages of high drug loading, platform stability, and ease of scaling-up, nanocrystals …
advantages of high drug loading, platform stability, and ease of scaling-up, nanocrystals …
[HTML][HTML] Formulation and development of oral fast-dissolving films loaded with nanosuspension to augment paroxetine bioavailability: In vitro characterization, ex vivo …
AH Elshafeey, RM El-Dahmy - Pharmaceutics, 2021 - mdpi.com
Paroxetine (PX) is the most potent serotonin reuptake inhibitor utilized in depression and
anxiety treatment. It has drawbacks, such as having a very bitter taste, low water solubility …
anxiety treatment. It has drawbacks, such as having a very bitter taste, low water solubility …
[HTML][HTML] Enhanced intradermal delivery of nanosuspensions of antifilariasis drugs using dissolving microneedles: a proof of concept study
Conventional oral administration of antifilariasis drugs results in nonspecific targeting of the
drugs and the intradermal delivery of nanoparticles with sizes of< 100 nm could be used to …
drugs and the intradermal delivery of nanoparticles with sizes of< 100 nm could be used to …
Establishment of In Vitro Dissolution Based on Similarity with In Vivo Dissolution: A Case Study on Aripiprazole
In vitro dissolution that predicts the in vivo performance of solid preparations is extremely
important in formulation optimization. Fraction absorbed (F a) has been used to screen in …
important in formulation optimization. Fraction absorbed (F a) has been used to screen in …
Safety of nanosuspensions in drug delivery
L Wang, J Du, Y Zhou, Y Wang - Nanomedicine: Nanotechnology, Biology …, 2017 - Elsevier
Nanosuspension technology is currently undergoing dramatic expansion in pharmaceutical
science research and development. However, most of the research efforts generally focus …
science research and development. However, most of the research efforts generally focus …
Brinzolamide nanocrystal formulations for ophthalmic delivery: reduction of elevated intraocular pressure in vivo
A Tuomela, P Liu, J Puranen, S Rönkkö… - International journal of …, 2014 - Elsevier
Nanocrystal-based drug delivery systems provide important tools for ocular formulation
development, especially when considering poorly soluble drugs. The objective of the study …
development, especially when considering poorly soluble drugs. The objective of the study …