Introduction: There has long been an interest in the effects of diet on mental health, and the
interaction of the two with stress; however, the nature of these relationships is not well …

The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …

Background The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the
endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence …

Stress causes or contributes to a huge variety of diseases and disorders. Recent evidence
suggests obesity and other eating-related disorders may be among these. Immediately after …

Mood disorders are serious diseases that affect a large portion of the population. There have
been many hypotheses put forth over the years to explain the development of major …

The a 28-amino acid peptide ghrelin was discovered in 1999 as a growth hormone (GH)
releasing peptide. Soon after its discovery, ghrelin was found to increase body weight and …

Most animals live under constant threat from predators, and predation has been a major
selective force in shaping animal behaviour. Nevertheless, defence responses against …

Blood biomarkers have been explored for their potential to provide objective measures in
the assessment of traumatic brain injury (TBI). However, it is not clear which biomarkers are …

Overnutrition is a risk factor for various human diseases, including neurodegenerative
diseases, metabolic disorders, and cancers. Therefore, targeting overnutrition represents a …

The hunger hormone ghrelin activates the ghrelin receptor GHSR to stimulate food intake
and growth hormone secretion and regulate reward signaling. Acylation of ghrelin at Ser3 is …