[HTML][HTML] The role and therapeutic implication of CPTs in fatty acid oxidation and cancers progression

J Wang, H Xiang, Y Lu, T Wu, G Ji - American Journal of Cancer …, 2021 - ncbi.nlm.nih.gov
Cancer cells must maintain metabolic homeostasis under a wide range of conditions and
meet their own energy needs in order to survive and reproduce. In addition to glycolysis …

Clinical and biochemical footprints of inherited metabolic disorders: X. Metabolic myopathies

C Angelini, A Burlina, N Blau, CR Ferreira - Molecular genetics and …, 2022 - Elsevier
Metabolic myopathies are characterized by the deficiency or dysfunction of essential
metabolites or fuels to generate energy for muscle contraction; they most commonly manifest …

[HTML][HTML] Mitochondrial carnitine palmitoyltransferase-II dysfunction: A possible novel mechanism for nonalcoholic fatty liver disease in hepatocarcinogenesis

M Yao, P Zhou, YY Qin, L Wang… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) or metabolic-associated fatty liver disease has
been characterized by the lipid accumulation with injury of hepatocytes and has become …

Muscle carnitine palmitoyltransferase II (CPT II) deficiency: a conceptual approach

PR Joshi, S Zierz - Molecules, 2020 - mdpi.com
Carnitine palmitoyltransferase (CPT) catalyzes the transfer of long-and medium-chain fatty
acids from cytoplasm into mitochondria, where oxidation of fatty acids takes place …

Metabolic lipid muscle disorders: biomarkers and treatment

C Angelini, E Pennisi, S Missaglia… - Therapeutic advances …, 2019 - journals.sagepub.com
Lipid storage myopathies (LSMs) are metabolic disorders of the utilization of fat in muscles
due to several different defects. In this review, a molecular update of LSMs is presented and …

Integrated 4D Analysis of Intramuscular Fat Deposition: Quantitative Proteomic and Transcriptomic Studies in Wannanhua Pig Longissimus Dorsi Muscle

X Li, F Xie, R Li, L Li, M Ren, M Jin, J Zhou, C Wang… - Animals, 2024 - mdpi.com
Simple Summary Wannanhua is a pig breed indigenous to Anhui Province, China. This
breed has a high intramuscular fat content, making it an ideal model for investigating lipid …

Myalgia in myositis and myopathies

S Glaubitz, K Schmidt, J Zschüntzsch… - Best Practice & Research …, 2019 - Elsevier
Myalgia is a common symptom of various neuromuscular disorders: myalgia occurs in
metabolic muscle diseases, inflammatory muscle diseases, dystrophic myopathies and …

Mitochondrial homeostasis mediates lipotoxicity in the failing myocardium

T Kretzschmar, JMF Wu, PC Schulze - International journal of molecular …, 2021 - mdpi.com
Heart failure remains the most common cause of death in the industrialized world. In spite of
new therapeutic interventions that are constantly being developed, it is still not possible to …

Circulatory response to exercise relative to oxygen uptake assessed in the follow‐up of patients with fatty acid beta‐oxidation disorders

A Imbard, H de Calbiac, E Le Guillou… - Journal of Inherited …, 2025 - Wiley Online Library
Patients with fatty acid oxidation disorders (FAODs) experience muscle symptoms due to
impaired ATP metabolism and the toxicity of accumulated mitochondrial FAO substrates or …

Diagnostic challenges in metabolic myopathies

C Angelini, R Marozzo, V Pegoraro… - Expert Review of …, 2020 - Taylor & Francis
Introduction Metabolic myopathies comprise a clinically etiological diverse group of
disorders caused by defects in cellular energy metabolism including the breakdown of …