Melatonin in cancer treatment: current knowledge and future opportunities
Melatonin is a pleotropic molecule with numerous biological activities. Epidemiological and
experimental studies have documented that melatonin could inhibit different types of cancer …
experimental studies have documented that melatonin could inhibit different types of cancer …
[HTML][HTML] A review of melatonin, its receptors and drugs
After a Turkish scientist took Nobel Prize due to his contributions to understand clock genes,
melatonin, closely related to these genes, may begin to shine. Melatonin, a hormone …
melatonin, closely related to these genes, may begin to shine. Melatonin, a hormone …
A review of the molecular aspects of melatonin's anti‐inflammatory actions: recent insights and new perspectives
Melatonin is a highly evolutionary conserved endogenous molecule that is mainly produced
by the pineal gland, but also by other nonendocrine organs, of most mammals including …
by the pineal gland, but also by other nonendocrine organs, of most mammals including …
Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling
Evidence is accumulating regarding the importance of circadian core oscillators, several
associated factors, and melatonin signaling in the maintenance of health. Dysfunction of …
associated factors, and melatonin signaling in the maintenance of health. Dysfunction of …
Melatonin signaling and cell protection function
Besides its well‐known regulatory role on circadian rhythm, the pineal gland hormone
melatonin has other biological functions and a distinct metabolism in various cell types and …
melatonin has other biological functions and a distinct metabolism in various cell types and …
Molecular mechanisms of the pro-apoptotic actions of melatonin in cancer: a review
M Bizzarri, S Proietti, A Cucina… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Compelling evidence has highlighted the complex pleiotropic functions elicited
by the melatonin in cancer cells. Melatonin behaves as a 'smart killer', ie, modulating anti …
by the melatonin in cancer cells. Melatonin behaves as a 'smart killer', ie, modulating anti …
Melatonin anticancer effects
G Di Bella, F Mascia, L Gualano, L Di Bella - International journal of …, 2013 - mdpi.com
Melatonin (N-acetyl-5-methoxytryptamine, MLT), the main hormone produced by the pineal
gland, not only regulates circadian rhythm, but also has antioxidant, anti-ageing and …
gland, not only regulates circadian rhythm, but also has antioxidant, anti-ageing and …
Melatonin in cancer management: progress and promise
B Jung, N Ahmad - Cancer research, 2006 - AACR
Physiologic and pharmacologic concentrations of the pineal hormone melatonin have
shown chemopreventive, oncostatic, and tumor inhibitory effects in a variety of in vitro and in …
shown chemopreventive, oncostatic, and tumor inhibitory effects in a variety of in vitro and in …
Melatonin and respiratory diseases: a review
S Habtemariam, M Daglia, A Sureda… - Current topics in …, 2017 - ingentaconnect.com
Melatonin is an indoleamine with potent multifunctional biological and pharmacological
effects, both receptor dependent and receptor-independent effects, including antioxidant …
effects, both receptor dependent and receptor-independent effects, including antioxidant …
Melatonin-induced methylation of the ABCG2/BCRP promoter as a novel mechanism to overcome multidrug resistance in brain tumour stem cells
Background: Current evidence indicates that a stem cell-like sub-population within
malignant glioblastomas, that overexpress members of the adenosine triphosphate-binding …
malignant glioblastomas, that overexpress members of the adenosine triphosphate-binding …