The design of new protein folds represents a grand challenge for synthetic, chemical and
structural biology. Due to the good understanding of the principles governing its pairing …

Protein oligomers are more common in nature than monomers, with dimers being the most
prevalent final structural state observed in known structures. From a biological perspective …

The spread of bacterial resistance to antibiotics poses the need for antimicrobial discovery.
With traditional search paradigms being exhausted, approaches that are altogether different …

Highlights•De novo single chain proteins can be designed with atomic accuracy.•Multi-chain
protein assemblies can be created based on different symmetries.•Extremely large …

Proteins are inherently limited by the properties of their constituent amino acids and attempt
to overcome this by using post translational modifications (PTMs). PTMs are highly specific …

In dieser Arbeit wurde eine neue Templat-gesteuerte fluorogene Peptidverknüpfung
vorgestellt. Speziell modifizierte Peptidfragmente wurden durch die Bindung an ein …

JI sl/en AI Tetraedrične kletke, ki jih tvorijo obvite vijačnice, so uspešen primer načrtovanja
proteinskih nanomaterialov. Cilj magistrske naloge je bil načrtovati, pripraviti in izolirati …

Antimicrobial resistance is a challenge facing the world in the twenty-first century with an
estimated 10 million deaths by 2050 if no actions are taken. Microbial resistance to drugs is …