Exploring the potential of solid dispersion for improving solubility, dissolution & bioavailability of herbal extracts, enriched fractions, and bioactives

D Mohapatra, AK Agrawal, AN Sahu - Journal of …, 2021 - Taylor & Francis
Most drugs' poor aqueous solubility has emerged as a significant challenge in achieving
proper therapeutic response following oral administration. Herbal drugs are being used from …

Nanoformulations of plant-derived compounds as emerging therapeutic approach for colorectal cancer

H Biganeh, SM Dizaji, YD Taghipour… - Current Drug …, 2023 - benthamdirect.com
Background: Colorectal cancer (CRC) represents one of the most daunting health problems
accompanied by progressive undesirable socio-economic effects. Phytochemicals, bioactive …

Fabrication and characterization of andrographolide analogue (3A. 1) nanosuspensions stabilized by amphiphilic chitosan derivatives for colorectal cancer therapy

T Kansom, W Sajomsang, R Saeeng… - Journal of Drug Delivery …, 2019 - Elsevier
Abstract Recently, 19-tert-butyldiphenylsilyl-8, 17-epoxy andrographolide (3A. 1) is an
andrographolide analogue which was a promising chemotherapeutic agent against some …

Investigating the effect of deacetylation temperature on the characterization of chitosan from crab shells as a candidate for organic nanofluids

R Ismail, DF Fitriyana, AP Bayuseno… - … Research in Fluid …, 2023 - semarakilmu.com.my
Chitosan has been broadly utilized in bone scaffold production because of its antibacterial
qualities, low toxicity, biodegradability, biocompatibility, and ability to aid regeneration …

[HTML][HTML] Polymer Matrix and Manufacturing Methods in Solid Dispersion System for Enhancing Andrographolide Solubility and Absorption: A Systematic Review

P Tipduangta, S Chansakaow, P Tansakul, R Meungjai… - Pharmaceutics, 2024 - mdpi.com
Background: Andrographolide (ADG) has poor aqueous solubility and low bioavailability.
This study systematically reviews the use of solid dispersion (SD) techniques to enhance the …

[PDF][PDF] Study on increasing solubility of isolates: methods and enhancement polymers

FDR NAFIS, AYC SRIWIDODO - Int J App Pharm, 2022 - academia.edu
Natural ingredients have been a source of medicine since ancient times. Research on the
development of natural ingredients as medicinal ingredients has increased. One of these is …

Development and in vitro evaluation of gel formulation of atorvastatin solid dispersions

AI Özdoğan, G Akca, S Şenel - Journal of Drug Delivery Science and …, 2021 - Elsevier
Atorvastatin is a statin group HMG-CoA reductase inhibitor drug that is commonly used to
adverse cardiovascular events and to lower blood total cholesterol and LDL-cholesterol. In …

Sintesis dan Karakterisasi Kitosan dari Limbah Kulit Udang Kaki Putih (Litopenaeus vannamei)

HN Imtihani, SN Permatasari - Jurnal Simbiosa, 2020 - repository.akfarsurabaya.ac.id
Udang kaki putih (Litopenaeus vannamei) merupakan salah satu krustasea yang banyak
dikomsumsi dan dibudidayakan di Indonesia sehingga menghasilkan banyak limbah kulit …

Preparation and characterization of Andrographis paniculata extract loaded onto chitosan-based nanoparticles

R Hasham, MY Ng, R Sabtu, MKH Idris… - Materials Today …, 2023 - Elsevier
Andrographis paniculata (AP) is a multipurpose medicinal herb native to Malaysia with
prominent anticancer properties. The main obstacles to its clinical value are ineffective drug …

Solid dispersion characteristics of whiteleg shrimp (Litopenaeus vannamei) extracted chitosan with hpmc and pvp k-30 as anti-cholesterol agents

HN Imtihani, SN Permatasari… - Research Journal of …, 2021 - indianjournals.com
This study aims at evaluating the characteristics of chitosan solid dispersion from whiteleg
shrimp (Litopenaeus vannamei). As anti-cholesterol agent, chitosan requires solubility …