Viral DNA genomes have limited coding capacity and therefore harness cellular factors to
facilitate replication of their genomes and generate progeny virions. Studies of viruses and …

The higher death rate caused by COVID-19 in older people, especially those with
comorbidities, is a challenge for biomedical aging research. Here we explore the idea that …

Immune system is a versatile and dynamic body organ which offers survival and endurance
of human beings in their hostile living environment. However, similar to other cells, immune …

The illness ME/CFS has been repeatedly tied to infectious agents such as Epstein Barr
Virus. Expanding research on the human microbiome now allows ME/CFS-associated …

Human B cells encompass functionally diverse lineages and phenotypic states that
contribute to protective as well as pathogenic responses. Epstein-Barr virus (EBV) provides …

Simple Summary Cellular senescence is considered a stress response that protects cells
against malignant transformation, facilitates tissue repair and development, and prevents …

Cellular senescence is a key biological process characterized by irreversible cell cycle
arrest. The accumulation of senescent cells creates a pro-inflammatory environment that can …

DNA damage response (DDR) and selective autophagy both can be activated by reactive
oxygen/nitrogen species (ROS/RNS), and both are of paramount importance in cancer …

Damage to our genomes triggers cellular senescence characterised by stable cell cycle
arrest and a pro-inflammatory secretome that prevents the unrestricted growth of cells with …

Epstein-Barr virus (EBV) immortalizes resting B-lymphocytes through a highly orchestrated
reprogramming of host chromatin structure, transcription and metabolism. Here, we use a …