[HTML][HTML] Molecular pathogenesis of subretinal fibrosis in neovascular AMD focusing on epithelial-mesenchymal transformation of retinal pigment epithelium

D Liu, C Zhang, J Zhang, GT Xu, J Zhang - Neurobiology of Disease, 2023 - Elsevier
Age-related macular degeneration (AMD) is a leading cause of vision loss among elderly
people in developed countries. Neovascular AMD (nAMD) accounts for more than 90% of …

The recent research progress of NF-κB signaling on the proliferation, migration, invasion, immune escape and drug resistance of glioblastoma

P Shi, J Xu, H Cui - International Journal of Molecular Sciences, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is the most common and invasive primary central nervous
system tumor in humans, accounting for approximately 45–50% of all primary brain tumors …

Chemical Transdifferentiation of Somatic Cells: Unleashing the Power of Small Molecules

Y Zhang, X Li, J Xing, J Zhou, H Li - Biomedicines, 2023 - mdpi.com
Chemical transdifferentiation is a technique that utilizes small molecules to directly convert
one cell type into another without passing through an intermediate stem cell state. This …

Evaluation of the molecular mechanism of chlorogenic acid in the treatment of pulmonary arterial hypertension based on analysis network pharmacology and …

JC Santos-Álvarez, JM Velázquez-Enríquez… - Journal of Vascular …, 2024 - mdpi.com
Background: Pulmonary arterial hypertension (PAH) is a serious disease characterized by
increased pressure in the pulmonary arteries, which can lead to heart failure and death …

[HTML][HTML] Oxidative Stress and Inflammation-Related mRNAs Are Elevated in Serum of a Finnish Wet AMD Cohort

M Liukkonen, H Heloterä, L Siintamo… - … & Visual Science, 2024 - tvst.arvojournals.org
Purpose: Localized diseases can be affected by and affect the systemic environment via
blood circulation. In this study, we explored the differences in circulating serum mRNAs …

[HTML][HTML] Single-cell and machine learning approaches uncover intrinsic immune-evasion genes in the prognosis of hepatocellular carcinoma

J Wang, X Chen, D Wu, C Jia, Q Lian, Y Pan, J Yang - Liver Research, 2024 - Elsevier
Background and aims Hepatocellular carcinoma (HCC) is a tumor of high heterogeneity and
complexity, which poses significant challenges to effective treatment and patient prognosis …