In order to directly functionalize C− H bonds of complex molecules and, in particular, to
control the regioselectivity of the reaction, a wide range of directing groups has been used …

An efficient method for the synthesis of bicyclic spirodiamine molecules via β-C (sp3)–H
bond activation of aliphatic amides, followed by cyclization with maleimides, has been …

Due to the high electrophilic nature of azo-dienophiles, azo-Diels–Alder proceeds rapidly
even without the need of a catalyst and is therefore regarded as the “click reaction”. This …

Herein, the density functional theory method was employed to investigate the mechanism of
the ligand-promoted divergent α, β-dehydrogenation of aliphatic acids. The calculated …

The transition metal-catalysed dicarbofunctionalisation of unactivated alkenes normally
requires exogenous strong coordinated directing groups, thus reducing the overall reaction …

Transient directing groups (TDGs) can be a powerful strategy for directly functionalizing C–H
bonds of aldehydes. We report a palladium-catalyzed oC–H alkoxycarbonylation of …

The Catellani-type palladium/norbornene-cocatalyzed ortho-amination of aryl halides has
been widely applied. Although a Pd (0)/Pd (II)/Pd (IV) mechanism is generally adopted …

Mechanistic proposals for the C–H activation reaction enabled by mono-N-protected amino
acid ligands (MPAAs) have been supported by DFT calculations. The direct experimental …

Base-assisted deprotonation was well acknowledged in versatile transition metal ion-
catalyzed C–H activation mechanisms. However, the pathway of deprotonation, that is …

Noncovalent interactions and the coordination bond-assisted capture of Pd (0) in
supramolecular cavities of bis (2, 4-bis (trichloromethyl)-1, 3, 5-triazapentadienato)-Pd (II) is …