Regulation of CAR and PXR Expression in Health and Disease
M Daujat-Chavanieu, S Gerbal-Chaloin - Cells, 2020 - mdpi.com
Pregnane X receptor (PXR, NR1I2) and constitutive androstane receptor (CAR, NR1I3) are
members of the nuclear receptor superfamily that mainly act as ligand-activated transcription …
members of the nuclear receptor superfamily that mainly act as ligand-activated transcription …
[HTML][HTML] PXR: a center of transcriptional regulation in cancer
Y Xing, J Yan, Y Niu - Acta Pharmaceutica Sinica B, 2020 - Elsevier
Abstract Pregnane X receptor (PXR, NR1I2) is a prototypical member of the nuclear receptor
superfamily. PXR can be activated by both endobiotics and xenobiotics. As a key xenobiotic …
superfamily. PXR can be activated by both endobiotics and xenobiotics. As a key xenobiotic …
[HTML][HTML] MicroRNAs and xenobiotic toxicity: an overview
S Balasubramanian, K Gunasekaran, S Sasidharan… - Toxicology reports, 2020 - Elsevier
The advent of new technologies has paved the rise of various chemicals that are being
employed in industrial as well as consumer products. This leads to the accumulation of …
employed in industrial as well as consumer products. This leads to the accumulation of …
Photocatalytic removal of diclofenac by Ti doped BiOI microspheres under visible light irradiation: kinetics, mechanism, and pathways
BiOI microspheres doped with different amounts of Ti were fabricated and used to remove
diclofenac (DCF) from water under visible light irradiation. The fabricated photocatalysts …
diclofenac (DCF) from water under visible light irradiation. The fabricated photocatalysts …
Bioaccumulation of abacavir and efavirenz in Rhinella arenarum tadpoles after exposure to environmentally relevant concentrations
LP Fernández, R Brasca, MR Repetti, AM Attademo… - Chemosphere, 2022 - Elsevier
Antiretrovirals are pharmaceuticals used in the treatment of the human immunodeficiency
virus; they are contaminants of emerging concern that have received considerable attention …
virus; they are contaminants of emerging concern that have received considerable attention …
Effects of triclosan on the RedoximiRs/Sirtuin/Nrf2/ARE signaling pathway in mosquitofish (Gambusia affinis)
S Bao, C He, P Ku, M Xie, J Lin, S Lu, X Nie - Aquatic Toxicology, 2021 - Elsevier
Triclosan (TCS) has been widely used in daily life for its broad-spectrum antibacterial
property and subsequently detected frequently in aquatic waterborne. Environmental …
property and subsequently detected frequently in aquatic waterborne. Environmental …
Atorvastatin causes oxidative stress and alteration of lipid metabolism in estuarine goby Mugilogobius abei
Y Wang, C Wang, M Xie, T Tang, Z Wang, X Nie - Environmental Pollution, 2021 - Elsevier
The potential effects of the environmental residues of Atorvastatin (ATV) as a widely used
antilipemic agent on aquatic organisms deserve more investigations because of its high …
antilipemic agent on aquatic organisms deserve more investigations because of its high …
Effects of atorvastatin on the Sirtuin/PXR signaling pathway in Mugilogobius chulae
Y Zhao, M Xie, C Wang, Y Wang, Y Peng… - … Science and Pollution …, 2023 - Springer
Atorvastatin (ATV) is a hypolipidemic drug widely detected in the aquatic environment.
Nevertheless, limited information is provided about the toxic effects of ATV on estuary or …
Nevertheless, limited information is provided about the toxic effects of ATV on estuary or …
[HTML][HTML] Impact of Metabolic disrupting chemicals on redox homeostasis, energy sensors, receptor modulation, and hormone metabolism: A comparative account in …
U Mukherjee, S Maitra - Aquaculture and Fisheries, 2024 - Elsevier
Endocrine-disrupting chemicals (EDCs) may mimic the endogenous neuroendocrine and
endocrine messengers and interfere with developmental, reproductive, immune, metabolic …
endocrine messengers and interfere with developmental, reproductive, immune, metabolic …
Hypoxia aggravates the burden of yellowstripe goby (Mugilogobius chulae) under atorvastatin exposure
Y Wang, T Tang, J Ren, Y Zhao, Y Hou, X Nie - Aquatic Toxicology, 2023 - Elsevier
In the present study, an estuarine benthic fish, Mugilogobius chulae (M. chulae), was
exposed to hypoxia, atorvastatin (ATV), a highly used and widely detected lipid-lowering …
exposed to hypoxia, atorvastatin (ATV), a highly used and widely detected lipid-lowering …