Perivascular spaces include a variety of passageways around arterioles, capillaries and
venules in the brain, along which a range of substances can move. Although perivascular …

Both type 1 and type 2 diabetes adversely affect the microvasculature in multiple organs.
Our understanding of the genesis of this injury and of potential interventions to prevent, limit …

摘要背景: 1 型糖尿病(Type 1 diabetes, T1D) 可能会对患者的大脑结构与功能产生重要的影响,
这被称为1 型糖尿病相关的认知能力下降(T1D‐associated cognitive decline, T1DACD) …

White matter hyperintensities (WMH) of presumed vascular origin, also referred to as
leukoaraiosis, are a very common finding on brain magnetic resonance imaging (MRI) or …

Small vessel diseases (SVDs) are a group of disorders that result from pathological
alteration of the small blood vessels in the brain, including the small arteries, capillaries and …

Background: Perivascular spaces (PVS) are an important component of cerebral small
vessel disease (SVD), several inflammatory disorders, hypertension and blood-brain barrier …

Background and Purpose—Enlarged perivascular spaces in the brain are common but
generally overlooked and of uncertain pathophysiology. They may reflect underlying …

Obesity is associated with increased risk for cardiovascular health problems including
diabetes, hypertension, and stroke. These cardiovascular afflictions increase risk for …

The deleterious effects of diabetes mellitus on the retinal, renal, cardiovascular, and
peripheral nervous systems are widely acknowledged. Less attention has been given to the …

The retinal and cerebral microvasculatures share many morphological and physiological
properties. Assessment of the cerebral microvasculature requires highly specialized and …