Iron is a critical component of many cellular functions including DNA replication and repair,
and it is essential for cell vitality. As an essential element, iron is critical for maintaining …

Iron is essential for all organisms and cells. Diseases of iron imbalance affect billions of
patients, including those with iron overload and other forms of iron toxicity. Excess iron load …

Background Dihydroquercetin (DHQ) is a flavonoid with strong anti-inflammatory and
antioxidant effects. However, its protective activity against cigarette smoke-induced …

Ferroptosis, an iron‐dependent cell death characterized by lethal lipid peroxidation, is
involved in chronic obstructive pulmonary disease (COPD) pathogenesis. Therefore …

Disturbances in mitochondrial structure and function in lung epithelial cells have been
implicated in the pathogenesis of various lung diseases, including chronic obstructive …

Clinical epidemiological studies have confirmed that tobacco smoking disrupts bone
homeostasis and is an independent risk factor for the development of osteoporosis. The low …

Quercetin is a flavonoid with antioxidant and anti-inflammatory properties. Quercetin has
potentially beneficial therapeutic effects for several diseases, including cigarette smoking …

Chronic obstructive pulmonary disease (COPD) is an increasing and major global health
problem. COPD is also the third leading cause of death worldwide. Oxidative stress (OS) …

Iron homeostasisis is integral to normal physiological and biochemical processes of lungs.
The maintenance of iron homeostasis involves the process of intake, storage and output …

Background Asbestos is a fibrous mineral that was widely used in the past. However,
asbestos inhalation is associated with an aggressive type of cancer known as malignant …