Staphylococci are commensal bacteria living on the epithelial surfaces of humans and other
mammals. Many staphylococci, including the dangerous pathogen Staphylococcus aureus …

Fibrinolytic enzymes are proteases responsible for cleavage of fibrin mesh in thrombus clots,
which are the primary causative agents in cardiovascular diseases. Developing safe …

Background Thrombolytic drugs are widely used for the management of cerebral venous
sinus thrombosis patients. Several in vitro models have been developed to study clot lytic …

Thrombotic disorders have emerged as serious threat to society. As anticoagulant and
thrombolytic therapies are usually associated with serious bleeding complications, the focus …

Background Optimal dosing of the recombinant tissue-type plasminogen activator (rt-PA) is
important in treating pulmonary thromboembolism (PTE). The aim of this study was to …

Background Atherothrombotic diseases such as myocardial or cerebral infarction are
serious consequences of the thrombus formed in blood vessels. Thrombolytic agents are …

Besides the well-known and wide use of ultrasound in diagnostics, the therapeutic use of
ultrasound has recently emerged. The understanding of the action of ultrasound waves at …

Inspired by microvesicle-mediated intercellular communication, we propose a hybrid vector
for magnetic drug delivery. It consists of macrophage-derived microvesicles engineered to …

Tissue plasminogen activator (tPA), a widely used thrombolytic agent, has an application
limit due to short half-life. To prolong the half-life of tPA, liposomes composed of egg …

Background A significant proportion of incident and prevalent hemodialysis patients have
central venous catheters for vascular access. No consensus is available on the prevention of …