Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …

Hyperpolarization chemistry based on reversible exchange of parahydrogen, also known as
Signal Amplification By Reversible Exchange (SABRE), is a particularly simple approach to …

Nuclear spin hyperpolarization enables real-time observation of metabolism and
intermolecular interactions in vivo. 1-13C-pyruvate is the leading hyperpolarized tracer …

Optically probed nitrogen-vacancy (NV)) quantum defects in diamond can detect nuclear
magnetic resonance (NMR) signals with high-spectral resolution from micron-scale sample …

Signal amplification by reversible exchange (SABRE) creates “hyperpolarization”(large spin
magnetization) using a transition metal catalyst and parahydrogen, addressing the …

Abstract Herein, we demonstrate “direct” 13C hyperpolarization of 13C‐acetate via signal
amplification by reversible exchange (SABRE). The standard SABRE homogeneous catalyst …

Abstract We introduce a Spin Transfer Automated Reactor (STAR) that produces continuous
parahydrogen induced polarization (PHIP), which is stable for hours to days. We use the …

NMR hyperpolarization techniques enhance nuclear spin polarization by several orders of
magnitude resulting in corresponding sensitivity gains. This enormous sensitivity gain …

Nuclear spin hyperpolarization is a quantum effect that enhances the nuclear magnetic
resonance signal by several orders of magnitude and has enabled real-time metabolic …

Metronidazole is a prospective hyperpolarized MRI contrast agent with potential hypoxia
sensing utility for applications in cancer, stroke, neurodegenerative diseases, etc. We …