Computational models for active matter
Active matter, which ranges from molecular motors to groups of animals, exists at different
length scales and timescales, and various computational models have been proposed to …
length scales and timescales, and various computational models have been proposed to …
Physical models of collective cell migration
Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …
Collective cell durotaxis emerges from long-range intercellular force transmission
The ability of cells to follow gradients of extracellular matrix stiffness—durotaxis—has been
implicated in development, fibrosis, and cancer. Here, we found multicellular clusters that …
implicated in development, fibrosis, and cancer. Here, we found multicellular clusters that …
Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers
JR Mayers, ME Torrence, LV Danai… - Science, 2016 - science.org
Tumor genetics guides patient selection for many new therapies, and cell culture studies
have demonstrated that specific mutations can promote metabolic phenotypes. However …
have demonstrated that specific mutations can promote metabolic phenotypes. However …
Mechanisms of neural crest migration
A Szabó, R Mayor - Annual Review of Genetics, 2018 - annualreviews.org
Neural crest cells are a transient embryonic cell population that migrate collectively to
various locations throughout the embryo to contribute a number of cell types to several …
various locations throughout the embryo to contribute a number of cell types to several …
Collective cell migration: a physics perspective
V Hakim, P Silberzan - Reports on Progress in Physics, 2017 - iopscience.iop.org
Cells have traditionally been viewed either as independently moving entities or as
somewhat static parts of tissues. However, it is now clear that in many cases, multiple cells …
somewhat static parts of tissues. However, it is now clear that in many cases, multiple cells …
Physical models of collective cell motility: from cell to tissue
In this article, we review physics-based models of collective cell motility. We discuss a range
of techniques at different scales, ranging from models that represent cells as simple self …
of techniques at different scales, ranging from models that represent cells as simple self …
Mechanisms and in vivo functions of contact inhibition of locomotion
B Stramer, R Mayor - Nature reviews Molecular cell biology, 2017 - nature.com
Contact inhibition of locomotion (CIL) is a process whereby a cell ceases motility or changes
its trajectory upon collision with another cell. CIL was initially characterized more than half a …
its trajectory upon collision with another cell. CIL was initially characterized more than half a …
Energetics of mesoscale cell turbulence in two-dimensional monolayers
Investigation of energy mechanisms at the collective cell scale is a challenge for
understanding various biological processes, such as embryonic development and tumor …
understanding various biological processes, such as embryonic development and tumor …
Rules of collective migration: from the wildebeest to the neural crest
A Shellard, R Mayor - Philosophical Transactions of the …, 2020 - royalsocietypublishing.org
Collective migration, the movement of groups in which individuals affect the behaviour of
one another, occurs at practically every scale, from bacteria up to whole species' …
one another, occurs at practically every scale, from bacteria up to whole species' …