Computational models for active matter

MR Shaebani, A Wysocki, RG Winkler… - Nature Reviews …, 2020 - nature.com
Active matter, which ranges from molecular motors to groups of animals, exists at different
length scales and timescales, and various computational models have been proposed to …

Physical models of collective cell migration

R Alert, X Trepat - Annual Review of Condensed Matter Physics, 2020 - annualreviews.org
Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …

Collective cell durotaxis emerges from long-range intercellular force transmission

R Sunyer, V Conte, J Escribano, A Elosegui-Artola… - Science, 2016 - science.org
The ability of cells to follow gradients of extracellular matrix stiffness—durotaxis—has been
implicated in development, fibrosis, and cancer. Here, we found multicellular clusters that …

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers

JR Mayers, ME Torrence, LV Danai… - Science, 2016 - science.org
Tumor genetics guides patient selection for many new therapies, and cell culture studies
have demonstrated that specific mutations can promote metabolic phenotypes. However …

Mechanisms of neural crest migration

A Szabó, R Mayor - Annual Review of Genetics, 2018 - annualreviews.org
Neural crest cells are a transient embryonic cell population that migrate collectively to
various locations throughout the embryo to contribute a number of cell types to several …

Collective cell migration: a physics perspective

V Hakim, P Silberzan - Reports on Progress in Physics, 2017 - iopscience.iop.org
Cells have traditionally been viewed either as independently moving entities or as
somewhat static parts of tissues. However, it is now clear that in many cases, multiple cells …

Physical models of collective cell motility: from cell to tissue

BA Camley, WJ Rappel - Journal of physics D: Applied physics, 2017 - iopscience.iop.org
In this article, we review physics-based models of collective cell motility. We discuss a range
of techniques at different scales, ranging from models that represent cells as simple self …

Mechanisms and in vivo functions of contact inhibition of locomotion

B Stramer, R Mayor - Nature reviews Molecular cell biology, 2017 - nature.com
Contact inhibition of locomotion (CIL) is a process whereby a cell ceases motility or changes
its trajectory upon collision with another cell. CIL was initially characterized more than half a …

Energetics of mesoscale cell turbulence in two-dimensional monolayers

SZ Lin, WY Zhang, D Bi, B Li, XQ Feng - Communications Physics, 2021 - nature.com
Investigation of energy mechanisms at the collective cell scale is a challenge for
understanding various biological processes, such as embryonic development and tumor …

Rules of collective migration: from the wildebeest to the neural crest

A Shellard, R Mayor - Philosophical Transactions of the …, 2020 - royalsocietypublishing.org
Collective migration, the movement of groups in which individuals affect the behaviour of
one another, occurs at practically every scale, from bacteria up to whole species' …