The glymphatic system in humans: investigations with magnetic resonance imaging

S Naganawa, T Taoka, R Ito… - Investigative …, 2024 - journals.lww.com
The concept of the glymphatic system was proposed more than a decade ago as a
mechanism for interstitial fluid flow and waste removal in the central nervous system. The …

[HTML][HTML] Novel developments in non-contrast enhanced MRI of the perivascular clearance system: What are the possibilities for Alzheimer's disease research?

MM van der Thiel, WH Backes, IHGB Ramakers… - Neuroscience & …, 2023 - Elsevier
The cerebral waste clearance system (ie, glymphatic or intramural periarterial drainage)
works through a network of perivascular spaces (PVS). Dysfunction of this system likely …

Usefulness of intravoxel incoherent motion MRI for visualizing slow cerebrospinal fluid motion

S Yamada, S Hiratsuka, T Otani, S Ii, S Wada… - Fluids and Barriers of …, 2023 - Springer
Background In the cerebrospinal fluid (CSF) dynamics, the pulsations of cerebral arteries
and brain is considered the main driving force for the reciprocating bidirectional CSF …

Diffusion magnetic resonance imaging of cerebrospinal fluid dynamics: Current techniques and future advancements

AM Wright, YC Wu, L Feng, Q Wen - NMR in Biomedicine, 2024 - Wiley Online Library
Cerebrospinal fluid (CSF) plays a critical role in metabolic waste clearance from the brain,
requiring its circulation throughout various brain pathways, including the ventricular system …

Current state of artificial intelligence in clinical applications for head and neck MR imaging

N Fujima, K Kamagata, D Ueda, S Fujita… - … Resonance in Medical …, 2023 - jstage.jst.go.jp
Due primarily to the excellent soft tissue contrast depictions provided by MRI, the
widespread application of head and neck MRI in clinical practice serves to assess various …

Diffusion tensor image analysis ALong the perivascular space (DTI-ALPS): revisiting the meaning and significance of the method

T Taoka, R Ito, R Nakamichi, T Nakane… - … Resonance in Medical …, 2024 - jstage.jst.go.jp
The ALPS-index was found to be an indicator of a number of conditions related to the
glymphatic system. Thus, although this was expected in the original report, the results of the …

Association between the putative meningeal lymphatics at the posterior wall of the sigmoid sinus and delayed contrast-agent elimination from the cerebrospinal fluid

S Naganawa, R Ito, M Kawamura, T Taoka… - … Resonance in Medical …, 2024 - jstage.jst.go.jp
Purpose: To investigate the characteristics of the putative meningeal lymphatics located at
the posterior wall of the sigmoid sinus (PML-PSS) in human subjects imaged before and …

Clinical magnetic resonance imaging evaluation of glymphatic function

ED Boyd, J Kaur, G Ding, M Chopp… - NMR in …, 2024 - Wiley Online Library
The glymphatic system is a system of specialized perivascular spaces in the brain that
facilitates removal of toxic waste solutes from the brain. Evaluation of glymphatic system …

Cerebrospinal fluid-based spatial statistics: towards quantitative analysis of cerebrospinal fluid pseudodiffusivity

Y Chen, H Hong, A Nazeri, HS Markus… - Fluids and Barriers of the …, 2024 - Springer
Background Cerebrospinal fluid (CSF) circulation is essential in removing metabolic wastes
from the brain and is an integral component of the glymphatic system. Abnormal CSF …

Low b-value diffusion tensor imaging to analyze the dynamics of cerebrospinal fluid: resolving intravoxel pseudorandom motion into ordered and disordered motions

Y Bito, H Ochi, R Shirase, W Yokohama… - … Resonance in Medical …, 2025 - jstage.jst.go.jp
Purpose: Analysis of cerebrospinal fluid (CSF) dynamics may be beneficial for
understanding the mechanisms and diagnosis of several neurological diseases. Low b …