Revisiting IL-2: Biology and therapeutic prospects
Interleukin-2 (IL-2), the first cytokine that was molecularly cloned, was shown to be a T cell
growth factor essential for the proliferation of T cells and the generation of effector and …
growth factor essential for the proliferation of T cells and the generation of effector and …
Coeliac disease
K Lindfors, C Ciacci, K Kurppa, KEA Lundin… - Nature reviews Disease …, 2019 - nature.com
Coeliac disease is an immune-mediated enteropathy against dietary gluten present in
wheat, rye and barley and is one of the most common lifelong food-related disorders …
wheat, rye and barley and is one of the most common lifelong food-related disorders …
European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease
S Husby, S Koletzko, IR Korponay-Szabó… - Journal of pediatric …, 2012 - journals.lww.com
Objective: Diagnostic criteria for coeliac disease (CD) from the European Society for
Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) were published in …
Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) were published in …
Ectopic lymphoid-like structures in infection, cancer and autoimmunity
C Pitzalis, GW Jones, M Bombardieri… - Nature Reviews …, 2014 - nature.com
Ectopic lymphoid-like structures often develop at sites of inflammation where they influence
the course of infection, autoimmune disease, cancer and transplant rejection. These …
the course of infection, autoimmune disease, cancer and transplant rejection. These …
The Oslo definitions for coeliac disease and related terms
Objective The literature suggests a lack of consensus on the use of terms related to coeliac
disease (CD) and gluten. Design A multidisciplinary task force of 16 physicians from seven …
disease (CD) and gluten. Design A multidisciplinary task force of 16 physicians from seven …
Celiac disease: a review of current concepts in pathogenesis, prevention, and novel therapies
JA Tye-Din, HJ Galipeau, D Agardh - Frontiers in pediatrics, 2018 - frontiersin.org
Our understanding of celiac disease and how it develops has evolved significantly over the
last half century. Although traditionally viewed as a pediatric illness characterized by …
last half century. Although traditionally viewed as a pediatric illness characterized by …
Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens
We performed a genome-wide association study (GWAS) of IgA nephropathy (IgAN), the
most common form of glomerulonephritis, with discovery and follow-up in 20,612 individuals …
most common form of glomerulonephritis, with discovery and follow-up in 20,612 individuals …
Spectrum of gluten-related disorders: consensus on new nomenclature and classification
A decade ago celiac disease was considered extremely rare outside Europe and, therefore,
was almost completely ignored by health care professionals. In only 10 years, key …
was almost completely ignored by health care professionals. In only 10 years, key …
[HTML][HTML] Celiac disease: prevalence, diagnosis, pathogenesis and treatment
N Gujral, HJ Freeman… - World journal of …, 2012 - ncbi.nlm.nih.gov
Celiac disease (CD) is one of the most common diseases, resulting from both environmental
(gluten) and genetic factors [human leukocyte antigen (HLA) and non-HLA genes]. The …
(gluten) and genetic factors [human leukocyte antigen (HLA) and non-HLA genes]. The …
Interleukin-21: a double-edged sword with therapeutic potential
R Spolski, WJ Leonard - Nature reviews Drug discovery, 2014 - nature.com
Interleukin-21 is a cytokine with broad pleiotropic actions that affect the differentiation and
function of lymphoid and myeloid cells. Since its discovery in 2000, a tremendous amount …
function of lymphoid and myeloid cells. Since its discovery in 2000, a tremendous amount …