Old and new beta-lactamase inhibitors: molecular structure, mechanism of action, and clinical use
The β-lactams have a central place in the antibacterial armamentarium, but the increasing
resistance to these drugs, especially among Gram-negative bacteria, is becoming one of the …
resistance to these drugs, especially among Gram-negative bacteria, is becoming one of the …
Managing Acinetobacter baumannii infections
J Garnacho-Montero, JF Timsit - Current opinion in infectious …, 2019 - journals.lww.com
Managing Acinetobacter baumannii infections : Current Opinion in Infectious Diseases
Managing Acinetobacter baumannii infections : Current Opinion in Infectious Diseases Log in or …
Managing Acinetobacter baumannii infections : Current Opinion in Infectious Diseases Log in or …
Portrait of a killer: Uncovering resistance mechanisms and global spread of Acinetobacter baumannii
AK Cain, M Hamidian - PLoS Pathogens, 2023 - journals.plos.org
Antibiotic resistance is a growing global concern in the field of medicine as it renders
bacterial infections difficult to treat and often more severe. Acinetobacter baumannii is a …
bacterial infections difficult to treat and often more severe. Acinetobacter baumannii is a …
β-lactam antibiotics and β-lactamase enzymes inhibitors, part 2: our limited resources
S Alfei, AM Schito - Pharmaceuticals, 2022 - mdpi.com
β-lactam antibiotics (BLAs) are crucial molecules among antibacterial drugs, but the
increasing emergence of resistance to them, developed by bacteria producing β-lactamase …
increasing emergence of resistance to them, developed by bacteria producing β-lactamase …
Virulence Potential and Treatment Options of Multidrug-Resistant (MDR) Acinetobacter baumannii
Acinetobacter baumannii is an opportunistic pathogen which is undoubtedly known for a
high rate of morbidity and mortality in hospital-acquired infections. A. baumannii causes life …
high rate of morbidity and mortality in hospital-acquired infections. A. baumannii causes life …
Treatment of patients with serious infections due to carbapenem‐resistant Acinetobacter baumannii: How viable are the current options?
JN O'Donnell, V Putra, TP Lodise - … : The Journal of Human …, 2021 - Wiley Online Library
This review critically appraises the published microbiologic and clinical data on the
treatment of patients with carbapenem‐resistant Acinetobacter baumannii infections …
treatment of patients with carbapenem‐resistant Acinetobacter baumannii infections …
The AbaR antibiotic resistance islands found in Acinetobacter baumannii global clone 1–structure, origin and evolution
M Hamidian, RM Hall - Drug Resistance Updates, 2018 - Elsevier
In multiply resistant Acinetobacter baumannii, complex transposons located in the
chromosomal comM gene carry antibiotic and heavy metal resistance determinants. For one …
chromosomal comM gene carry antibiotic and heavy metal resistance determinants. For one …
Durlobactam, a Broad-Spectrum Serine β-lactamase Inhibitor, Restores Sulbactam Activity Against Acinetobacter Species
KM Papp-Wallace, SM McLeod… - Clinical Infectious …, 2023 - academic.oup.com
Sulbactam-durlobactam is a pathogen-targeted β-lactam/β-lactamase inhibitor combination
in late-stage development for the treatment of Acinetobacter infections, including those …
in late-stage development for the treatment of Acinetobacter infections, including those …
[HTML][HTML] In vitro activity of sulbactam-durlobactam against carbapenem-resistant Acinetobacter baumannii and mechanisms of resistance
J Findlay, L Poirel, M Bouvier, P Nordmann - Journal of Global …, 2022 - Elsevier
ABSTRACT Objectives Multidrug-resistant Acinetobacter baumannii (MDR-Ab), particularly
strains producing oxacillinase (OXA)-type carbapenemases, have rapidly emerged in health …
strains producing oxacillinase (OXA)-type carbapenemases, have rapidly emerged in health …
In vitro activity of sulbactam/durlobactam against global isolates of carbapenem-resistant Acinetobacter baumannii
H Seifert, C Müller, D Stefanik… - Journal of …, 2020 - academic.oup.com
Objectives To evaluate the activity of the novel broad-spectrum serine β-lactamase inhibitor
durlobactam (ETX2514) combined with sulbactam against global isolates of carbapenem …
durlobactam (ETX2514) combined with sulbactam against global isolates of carbapenem …