Horizontal gene transfer of antibiotic resistance genes in biofilms

C Michaelis, E Grohmann - Antibiotics, 2023 - mdpi.com
Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix
which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it …

Smart microneedle patches for wound healing and management

F Hu, Q Gao, J Liu, W Chen, C Zheng, Q Bai… - Journal of Materials …, 2023 - pubs.rsc.org
The number of patients with non-healing wounds is generally increasing globally, placing a
huge social and economic burden on every country. The complexity of the wound-healing …

Polycaprolactone–MXene nanofibrous scaffolds for tissue engineering

K Diedkova, AD Pogrebnjak, S Kyrylenko… - … applied materials & …, 2023 - ACS Publications
New conductive materials for tissue engineering are needed for the development of
regenerative strategies for nervous, muscular, and heart tissues. Polycaprolactone (PCL) is …

A dissolving microneedle patch for antibiotic/enzymolysis/photothermal triple therapy against bacteria and their biofilms

X Yu, J Zhao, D Fan - Chemical Engineering Journal, 2022 - Elsevier
The biofilms present in wounds are difficult to eliminate due to the compact barrier formed by
extracellular polymeric substances (EPS). Herein, we have designed a dissolvable …

Antibiotic delivery strategies to treat skin infections when innate antimicrobial defense fails

R Smith, J Russo, J Fiegel, N Brogden - Antibiotics, 2020 - mdpi.com
The epidermal skin barrier protects the body from a host of daily challenges, providing
protection against mechanical insults and the absorption of chemicals and xenobiotics. In …

Enzymolysis and photothermal-mediated synergistic antimicrobial nanoplatform with programmed EPS degradation and biofilm penetration capabilities for eradication …

D Qiu, C Zheng, Y Zeng, L Wu, C Huang, Y Ran… - Chemical Engineering …, 2023 - Elsevier
It is an effective method of eradicating biofilm infection and promoting wound healing by
exopolysaccharides (EPS) degradation and penetration of antimicrobial agents into biofilms …

Release mechanisms and molecular interactions of Pseudomonas aeruginosa extracellular DNA

S Sarkar - Applied Microbiology and Biotechnology, 2020 - Springer
Pseudomonas aeruginosa infection is a significant threat for clinicians. Increasing incidents
of resistant biofilm infection result in high mortality rates worldwide. There is a considerable …

Antiseptic agents for chronic wounds: a systematic review

K Barrigah-Benissan, J Ory, A Sotto, F Salipante… - Antibiotics, 2022 - mdpi.com
In many parts of the world, antiseptic agents remain non-indicated in chronic wound care. In
the current context of bacterial resistance to antibiotics and the development of new …

Correlation of crystal violet biofilm test results of Staphylococcus aureus clinical isolates with Raman spectroscopic read‐out

C Ebert, L Tuchscherr, N Unger… - Journal of Raman …, 2021 - Wiley Online Library
Biofilm‐related infections occur quite frequently in hospital settings and require rapid
diagnostic identification as they are recalcitrant to antibiotic therapy and make special …

[HTML][HTML] Host responses to mucosal biofilms in the lung and gut

JC Domingue, JL Drewes, CA Merlo, F Housseau… - Mucosal …, 2020 - Elsevier
The impact of the human microbiome on health and disease is of utmost importance and has
been studied intensively in recent years. Microbes promote immune system development …