CytoMAP: a spatial analysis toolbox reveals features of myeloid cell organization in lymphoid tissues

CR Stoltzfus, J Filipek, BH Gern, BE Olin, JM Leal… - Cell reports, 2020 - cell.com
Recently developed approaches for highly multiplexed imaging have revealed complex
patterns of cellular positioning and cell-cell interactions with important roles in both cellular …

Multiplexed imaging of human tuberculosis granulomas uncovers immunoregulatory features conserved across tissue and blood

EF McCaffrey, M Donato, L Keren, Z Chen… - Biorxiv, 2020 - biorxiv.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis that is
distinctly characterized by granuloma formation within infected tissues. Granulomas are …

[HTML][HTML] Mucosal vaccination with cyclic dinucleotide adjuvants induces effective T cell homing and IL-17–dependent protection against mycobacterium tuberculosis …

RM Jong, E Van Dis, SB Berry, X Nguyenla… - The Journal of …, 2022 - journals.aai.org
Tuberculosis consistently causes more deaths worldwide annually than any other single
pathogen, making new effective vaccines an urgent priority for global public health. Among …

Mathematical modeling suggests cooperation of plant-infecting viruses

J Miller, TM Burch-Smith, VV Ganusov - Viruses, 2022 - mdpi.com
Viruses are major pathogens of agricultural crops. Viral infections often start after the virus
enters the outer layer of a tissue, and many successful viruses, after local replication in the …

Examining Early Interactions Between Innate Airway Resident Immune Cells and Mtb-Specific Factors During Pulmonary Infection with Mycobacterium Tuberculosis

MD Dunlap - 2020 - search.proquest.com
Mycobacterium tuberculosis (Mtb) is the leading cause of death by an infectious agent in the
world today, infecting roughly one quarter of humans. Despite this, the mechanisms of early …